{"id":"W2885865993","doi":"10.1038/s41375-018-0229-3","title":"Genomic prediction of relapse in recipients of allogeneic haematopoietic stem cell transplantation","year":2018,"lang":"en","type":"article","venue":"Leukemia","topic":"Hematopoietic Stem Cell Transplantation","field":"Medicine","cited_by":16,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"China Scholarship Council; Tekes; Academy of Finland","keywords":"Transplantation; Human leukocyte antigen; Oncology; Biology; Haematopoiesis; Population; Exome sequencing; Stem cell; Internal medicine; Immunology; Medicine; Bioinformatics; Genetics; Gene; Antigen","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002782074,0.0001311653,0.0003451943,0.0002215113,0.00001958476,0.000002465054,0.00008493804,0.0001643597,0.0001018034],"category_scores_gemma":[0.000006092737,0.0001290665,0.00007316865,0.000255205,0.0001072765,0.00006251023,0.000007009804,0.0001171051,0.00005568343],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002512051,"about_ca_system_score_gemma":0.0001952947,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00008540123,"about_ca_topic_score_gemma":0.00002510622,"domain_scores_codex":[0.9985349,0.00006718392,0.0006865044,0.0002394797,0.0002888152,0.0001831403],"domain_scores_gemma":[0.9992864,0.00006875701,0.000197068,0.0002740926,0.0001056746,0.00006798723],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0007371298,0.0001457423,0.3268233,0.002145468,0.00003569447,0.00004351566,0.007175381,0.00009022458,0.6614992,0.0001129593,0.00007203698,0.001119349],"study_design_scores_gemma":[0.002950562,0.0004194317,0.4786876,0.0006923411,0.0001625176,0.0001094104,0.0001948559,0.0004891008,0.5161179,0.00005697192,0.00003773092,0.0000816145],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9934564,0.00009713172,0.001385721,0.00002034713,0.0002299076,0.0004620299,0.00004512439,0.00002761043,0.004275776],"genre_scores_gemma":[0.9981862,0.0002115007,0.001139316,0.00003027653,0.00004887947,0.00001591023,0.00007215665,0.00002459342,0.0002711598],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1518643,"threshold_uncertainty_score":0.526318,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0184548152876578,"score_gpt":0.2451735464951082,"score_spread":0.2267187312074504,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}