{"id":"W2885977543","doi":"10.1126/sciimmunol.aao4747","title":"Neutrophil cytoplasts induce T <sub>H</sub> 17 differentiation and skew inflammation toward neutrophilia in severe asthma","year":2018,"lang":"en","type":"article","venue":"Science Immunology","topic":"Asthma and respiratory diseases","field":"Medicine","cited_by":238,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Center for Advancing Translational Sciences; Eunice Kennedy Shriver National Institute of Child Health and Human Development; National Heart, Lung, and Blood Institute; Canadian Institutes of Health Research","keywords":"Neutrophilia; Inflammation; Cytoplast; Immunology; Asthma; Biology; Cell biology; Medicine; Cytoplasm","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001657583,0.0001504043,0.0001889853,0.0001393634,0.0001516355,0.0004275309,0.00007102286,0.0002295919,0.001918719],"category_scores_gemma":[0.000244695,0.0001331234,0.0001818178,0.00006317863,0.0003266945,0.0002125264,0.0003589078,0.0005396118,0.0004079659],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001932944,"about_ca_system_score_gemma":0.0001560734,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002948846,"about_ca_topic_score_gemma":0.0007087435,"domain_scores_codex":[0.9998583,0.00003849932,0.0000137866,0.00002210667,0.0000287183,0.00003851188],"domain_scores_gemma":[0.9998481,0.00002955105,0.00004281175,0.00002011355,0.00001344702,0.00004587077],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0007649585,0.0000616121,0.009141936,0.00006302622,0.00001431655,0.0004107131,0.0001049994,0.00008396379,0.9839674,0.0002086347,0.0002281076,0.004950501],"study_design_scores_gemma":[0.0002319251,0.003149832,0.3454691,0.00006083675,0.0000745898,0.004680051,0.0009326451,0.001682131,0.6358253,0.0007573505,0.00711468,0.00002151462],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9971765,0.001129689,0.000564477,0.0001028293,0.00003553006,0.0000180678,0.0001330324,0.00003039702,0.0008094514],"genre_scores_gemma":[0.9983405,0.0003255456,0.000308606,0.00005693549,0.00001904027,0.00001270463,0.0002301531,0.000007142383,0.0006993318],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001918719,"threshold_uncertainty_score":0.006418824,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01065432378443271,"score_gpt":0.2507260463691526,"score_spread":0.2400717225847199,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}