{"id":"W2886023660","doi":"10.1158/1538-7445.am2018-21","title":"Abstract 21: p66ShcA is a contextual breast cancer metastasis promoter or suppressor depending on the tumor microenvironment","year":2018,"lang":"en","type":"article","venue":"Cancer Research","topic":"Cancer Genomics and Diagnostics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Occupational Cancer Research Centre; McGill University; Jewish General Hospital","funders":"","keywords":"Breast cancer; Metastasis; Cancer research; Cancer; Metastatic breast cancer; Mammary tumor; Medicine; Pathology; Primary tumor; Lung cancer; Biology; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008867928,0.0003509259,0.0002066093,0.0002468096,0.0002188219,0.000367633,0.0001515097,0.000244935,0.006743405],"category_scores_gemma":[0.00009122949,0.0001201243,0.0002305883,0.0001934355,0.0002526396,0.0001289381,0.0002883875,0.0006137734,0.00101231],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002231686,"about_ca_system_score_gemma":0.0002184725,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000585766,"about_ca_topic_score_gemma":0.0007361286,"domain_scores_codex":[0.9998703,0.000010295,0.000009656694,0.00003649894,0.00004432574,0.00002888118],"domain_scores_gemma":[0.9998556,0.00002219822,0.00004277962,0.00001497628,0.00001282322,0.00005151318],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0000718673,0.00001428789,0.0003026229,0.00002165364,0.000002173336,0.00004953179,0.000005556041,0.00001989926,0.9987147,0.00006125349,0.00006384693,0.0006725439],"study_design_scores_gemma":[0.00002268614,0.0002211045,0.01359133,0.000009253225,0.00001938571,0.0008153822,0.00004387956,0.0007343652,0.9801586,0.00009001279,0.004287389,0.000006576378],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9908918,0.0009769821,0.003452154,0.0002039483,0.0000659591,0.00003991121,0.001739472,0.0002851587,0.002344786],"genre_scores_gemma":[0.9922018,0.000365618,0.001150521,0.00006015975,0.00001219687,0.00003239321,0.001323549,0.0000458685,0.004807927],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.006743405,"threshold_uncertainty_score":0.02255893,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06123376126744564,"score_gpt":0.3640722943682793,"score_spread":0.3028385331008336,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}