{"id":"W2886087618","doi":"10.1158/1538-7445.am2018-3359","title":"Abstract 3359: Elucidating the oncogenic mechanism of the TAZ-CAMTA1 and YAP-TFE3 fusion proteins","year":2018,"lang":"en","type":"article","venue":"Cancer Research","topic":"Hippo pathway signaling and YAP/TAZ","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Mount Sinai Hospital","funders":"","keywords":"Hippo signaling pathway; Fusion protein; Fusion gene; Biology; Cancer research; Sarcoma; Cancer; Cell biology; Pathology; Gene; Signal transduction; Medicine; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000182074,0.0003442012,0.0001236347,0.0002882509,0.0002265503,0.0001961164,0.0003260389,0.0003582556,0.002575039],"category_scores_gemma":[0.000108662,0.0001068328,0.0003228745,0.0002794045,0.0002276946,0.0002594,0.0001703371,0.0006585895,0.001047989],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006478664,"about_ca_system_score_gemma":0.0003576579,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001622955,"about_ca_topic_score_gemma":0.001080662,"domain_scores_codex":[0.9999149,0.000007866025,0.000005208743,0.00001520273,0.00003644108,0.00002036035],"domain_scores_gemma":[0.9999565,0.000007495253,0.00001183127,0.00000335282,0.00000915873,0.00001170535],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0000785574,0.00003087816,0.0002104297,0.00004908347,0.000004595729,0.0001118093,0.00001111391,0.00008663859,0.9974135,0.000360725,0.00018731,0.001455299],"study_design_scores_gemma":[0.00002937067,0.0001906872,0.004394622,0.000008930818,0.00001765292,0.0009711726,0.00002755998,0.001909432,0.9815984,0.0001751885,0.01067084,0.000006149692],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9659811,0.003877754,0.01803561,0.001062869,0.00008074745,0.0002140675,0.004159083,0.0002171274,0.006371669],"genre_scores_gemma":[0.963566,0.002987806,0.01575593,0.0001597253,0.00002715334,0.000142819,0.008775915,0.00004638405,0.008538283],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002575039,"threshold_uncertainty_score":0.008614361,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05366519701349143,"score_gpt":0.3663978581423943,"score_spread":0.3127326611289029,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}