{"id":"W2886127930","doi":"10.1002/anie.201806966","title":"Site‐Selective, Late‐Stage C−H <sup>18</sup>F‐Fluorination on Unprotected Peptides for Positron Emission Tomography Imaging","year":2018,"lang":"en","type":"article","venue":"Angewandte Chemie International Edition","topic":"Fluorine in Organic Chemistry","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":94,"is_retracted":false,"has_abstract":true,"ca_institutions":"Simon Fraser University; BC Cancer Agency; TRIUMF","funders":"Canadian Cancer Society Research Institute; Michael Smith Health Research BC; Natural Sciences and Engineering Research Council of Canada; F. Hoffmann-La Roche","keywords":"Positron emission tomography; Brain positron emission tomography; Radiochemistry; Positron emission; Stage (stratigraphy); Positron; Emission computed tomography; Physics; Nuclear medicine; Chemistry; Preclinical imaging; Materials science; Nuclear physics; Medicine; Geology; Electron; In vivo; Biology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001793955,0.0002971992,0.0001612543,0.00009700729,0.0001090932,0.0001708529,0.0002094862,0.0002763141,0.001181146],"category_scores_gemma":[0.0001454168,0.0001076372,0.0001176667,0.00008516065,0.0002044568,0.0002393706,0.0001459065,0.0003069727,0.0003435713],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000172036,"about_ca_system_score_gemma":0.0001469928,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003671913,"about_ca_topic_score_gemma":0.0006232472,"domain_scores_codex":[0.9999218,0.00001244854,0.000004015149,0.00002260059,0.00001899054,0.00002014775],"domain_scores_gemma":[0.9999208,0.00002334838,0.0000232934,0.000008185993,0.00001216933,0.00001224142],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004084995,0.000005064881,0.00004233261,0.00002295431,0.000001501431,0.00003809679,0.00001076276,0.00004542224,0.9981537,0.00008793104,0.00005050587,0.001500826],"study_design_scores_gemma":[0.000003991833,0.00005167705,0.0002198078,0.000001240368,0.000001494367,0.0001140327,0.000003509806,0.0002081511,0.9983468,0.00001408611,0.001032808,0.000002197822],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9671319,0.002884578,0.0236036,0.0001934785,0.00006548904,0.00006527803,0.0002011098,0.0002307642,0.005623788],"genre_scores_gemma":[0.9811177,0.001292994,0.01419216,0.0001011926,0.00002031908,0.00003696677,0.0001452958,0.00003768143,0.003055668],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001181146,"threshold_uncertainty_score":0.003951371,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04343141452261542,"score_gpt":0.3784813353702648,"score_spread":0.3350499208476494,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}