{"id":"W2886144338","doi":"10.1101/384792","title":"HERI-1 is a Chromodomain Protein that Negatively Regulates Transgenerational Epigenetic Inheritance","year":2018,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Genetics, Aging, and Longevity in Model Organisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"","keywords":"RNA interference; Chromodomain; Biology; Genetics; Epigenetics; Gene silencing; Gene; Phenocopy; Genetic screen; RNA silencing; Mutant; Cell biology; RNA","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008489365,0.0004083809,0.0001820947,0.0001885289,0.0001892607,0.0002189073,0.0003862902,0.000333962,0.002112759],"category_scores_gemma":[0.00007902794,0.0001369813,0.0002109886,0.00009899448,0.0002445781,0.0001494181,0.0002275594,0.0005532127,0.0009527303],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005455225,"about_ca_system_score_gemma":0.0001711988,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004565383,"about_ca_topic_score_gemma":0.000920875,"domain_scores_codex":[0.9998935,0.000005501915,0.000005535219,0.00003386215,0.00004108586,0.00002043428],"domain_scores_gemma":[0.9998827,0.00001646019,0.00004198442,0.000009065458,0.00001155473,0.00003819198],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002026952,0.000009730025,0.0001569296,0.00001565983,0.000002070562,0.00006079174,0.000002085792,0.00003825135,0.9988818,0.00006110946,0.00006296966,0.0006884183],"study_design_scores_gemma":[0.00002520802,0.0001206482,0.00941774,0.00001006771,0.00001520667,0.0007415083,0.00001677656,0.00280483,0.9801983,0.00007320929,0.006567163,0.00000919438],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9798201,0.004169033,0.008624862,0.0002837505,0.0001404901,0.00005379374,0.001479427,0.0004745394,0.004953949],"genre_scores_gemma":[0.9856722,0.0008084152,0.003092825,0.0001085532,0.00001752816,0.00002535339,0.001394561,0.00005331479,0.008827291],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002112759,"threshold_uncertainty_score":0.007067859,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01628916023989119,"score_gpt":0.2160321607019511,"score_spread":0.1997430004620599,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}