{"id":"W2886167575","doi":"10.1172/jci.insight.121364","title":"Survival in males with glioma and gastric adenocarcinoma correlates with mutant p53 residual transcriptional activity","year":2018,"lang":"en","type":"article","venue":"JCI Insight","topic":"Cancer-related Molecular Pathways","field":"Medicine","cited_by":17,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; Sunnybrook Health Science Centre","funders":"Canadian Institutes of Health Research","keywords":"Hazard ratio; Glioma; Mutant; Internal medicine; Medicine; Cancer; Germline mutation; Adenocarcinoma; Oncology; Mutation; Multivariate analysis; Biology; Cancer research; Gastroenterology; Gene; Genetics; Confidence interval","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003115592,0.0002047662,0.0002360687,0.0004568436,0.0002211805,0.0003290027,0.0001491734,0.0001947047,0.002345893],"category_scores_gemma":[0.001123963,0.0001298432,0.0004446469,0.0003798293,0.0001995169,0.0001863055,0.0003433113,0.0003315583,0.000290544],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001353348,"about_ca_system_score_gemma":0.0001923635,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00119364,"about_ca_topic_score_gemma":0.00183402,"domain_scores_codex":[0.9998229,0.00002910332,0.0000123699,0.0000563495,0.00003163843,0.0000476793],"domain_scores_gemma":[0.9991233,0.0001163518,0.0004351925,0.0000849362,0.00005621536,0.0001840154],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0001183221,0.000004042855,0.9982066,0.000002407035,0.00002591486,0.00008187618,0.00001450131,0.00003439394,0.0003710444,0.0000104446,0.00004485721,0.001085599],"study_design_scores_gemma":[0.000002103842,0.00007724236,0.9988674,0.000001690233,0.00002619476,0.0006731502,0.00004460442,0.00009764043,0.00009536913,0.00001867604,0.0000943784,0.000001484165],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9993717,0.0001519978,0.00006489399,0.00002851796,0.00000341646,0.000001096254,0.0002069733,0.000004768658,0.0001666379],"genre_scores_gemma":[0.999622,0.00005480746,0.00002967143,0.000006110114,0.000005514892,0.000001030241,0.0002127884,0.000001259325,0.00006687389],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002345893,"threshold_uncertainty_score":0.007847786,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01750451422611293,"score_gpt":0.2304037333594106,"score_spread":0.2128992191332976,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}