{"id":"W2886167575","doi":"10.1172/jci.insight.121364","title":"Survival in males with glioma and gastric adenocarcinoma correlates with mutant p53 residual transcriptional activity","year":2018,"lang":"en","type":"article","venue":"JCI Insight","topic":"Cancer-related Molecular Pathways","field":"Medicine","cited_by":17,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; Sunnybrook Health Science Centre","funders":"Canadian Institutes of Health Research","keywords":"Hazard ratio; Glioma; Mutant; Internal medicine; Medicine; Cancer; Germline mutation; Adenocarcinoma; Oncology; Mutation; Multivariate analysis; Biology; Cancer research; Gastroenterology; Gene; Genetics; Confidence interval","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001155812,0.0002353131,0.000334072,0.0002890251,0.00008187933,0.00002567558,0.00006402197,0.0001458955,0.0001001799],"category_scores_gemma":[0.00002382012,0.0001718393,0.00003260162,0.0005842223,0.0003720541,0.0001375651,0.00002371568,0.0003675807,0.00001756344],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001256112,"about_ca_system_score_gemma":0.0002811455,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001637989,"about_ca_topic_score_gemma":0.001254812,"domain_scores_codex":[0.9985561,0.00006883129,0.0001853495,0.0004366529,0.0004260385,0.0003270058],"domain_scores_gemma":[0.9993356,0.00005088683,0.0000721949,0.0002613894,0.0001181252,0.0001618309],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.01202982,0.0007103793,0.4873005,0.000155795,0.0003323013,0.004323565,0.002900503,0.00002835426,0.4883128,0.001212732,0.0001903881,0.002502969],"study_design_scores_gemma":[0.006231335,0.00367928,0.9372022,0.0003532114,0.0001738629,0.002600982,0.0001701542,0.0002705021,0.04796261,0.0000362938,0.001018447,0.0003011174],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9947749,0.000889241,0.0005651282,0.0005304346,0.0001323894,0.0004016501,0.00002088285,0.00006107135,0.002624253],"genre_scores_gemma":[0.9988986,0.00003384546,0.0005755847,0.00007444607,0.0001936734,0.00002285413,0.00001834985,0.00004428246,0.0001383263],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.4499018,"threshold_uncertainty_score":0.7007402,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01750451422611293,"score_gpt":0.2304037333594106,"score_spread":0.2128992191332976,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}