{"id":"W2886230072","doi":"10.1002/hipo.23001","title":"Altered hippocampal GABA and glutamate levels and uncoupling from functional connectivity in multiple sclerosis","year":2018,"lang":"en","type":"article","venue":"Hippocampus","topic":"Multiple Sclerosis Research Studies","field":"Medicine","cited_by":42,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; Montreal Neurological Institute and Hospital","funders":"National Institute of Biomedical Imaging and Bioengineering; National Institutes of Health; National Natural Science Foundation of China","keywords":"Glutamatergic; Hippocampal formation; Glutamate receptor; Neuroscience; Hippocampus; Neurotransmission; Excitatory postsynaptic potential; Psychology; Multiple sclerosis; gamma-Aminobutyric acid; Functional magnetic resonance imaging; Inhibitory postsynaptic potential; Chemistry; Medicine; Internal medicine; Psychiatry; Receptor","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001341493,0.0001793695,0.0001712288,0.0005705103,0.0001977078,0.0002008164,0.00009632242,0.0001722838,0.0006910142],"category_scores_gemma":[0.0004665749,0.0001276497,0.00008961044,0.0002566316,0.0002810023,0.000174324,0.000188651,0.0001432395,0.0000566437],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001474055,"about_ca_system_score_gemma":0.00009403141,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001565955,"about_ca_topic_score_gemma":0.003240718,"domain_scores_codex":[0.9999471,0.00001356908,0.000008632466,0.00001272187,0.00001120309,0.000006794342],"domain_scores_gemma":[0.9998349,0.00003117281,0.00008223247,0.00001384168,0.0000158989,0.00002196852],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.003289289,0.0002108896,0.8554666,0.0002298686,0.0005521721,0.001644699,0.001064065,0.0006449507,0.1100118,0.0001571554,0.000168331,0.02656018],"study_design_scores_gemma":[0.00002283722,0.0002616522,0.9954164,0.000005580066,0.00005182104,0.001258251,0.0001546422,0.0001715597,0.002428028,0.000154868,0.00007051029,0.000003875308],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9996953,0.0001499955,0.00003492506,0.000007225673,5.22434e-7,0.000001405453,0.00001307578,0.000001410848,0.00009611994],"genre_scores_gemma":[0.9998137,0.00007482817,0.00005391841,0.000005782756,0.000001385724,0.000001533807,0.00001803662,5.437499e-7,0.00003016782],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001565955,"threshold_uncertainty_score":0.003113627,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1200374660080454,"score_gpt":0.2977810876879096,"score_spread":0.1777436216798642,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}