{"id":"W2886314298","doi":"10.1093/hmg/ddy250","title":"Dystonin-A3 upregulation is responsible for maintenance of tubulin acetylation in a less severe<i>dystonia musculorum</i>mouse model for hereditary sensory and autonomic neuropathy type VI","year":2018,"lang":"en","type":"article","venue":"Human Molecular Genetics","topic":"Hereditary Neurological Disorders","field":"Neuroscience","cited_by":9,"is_retracted":false,"has_abstract":true,"ca_institutions":"Ottawa Hospital; University of Ottawa","funders":"Canadian Institutes of Health Research; Department of Science and Technology, Ministry of Science and Technology, India; Canadian Institute for Advanced Research","keywords":"Biology; Microtubule; Gene isoform; Downregulation and upregulation; Acetylation; Neuroscience; Endocrinology; Cell biology; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001963864,0.0007484105,0.0003964355,0.0007363977,0.0004103331,0.0005165499,0.0004701143,0.0009949943,0.003914974],"category_scores_gemma":[0.0001558275,0.0003502547,0.0007293932,0.0002567566,0.0005598296,0.0002895794,0.0003261626,0.001527297,0.0009543093],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006668993,"about_ca_system_score_gemma":0.0003548248,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001811358,"about_ca_topic_score_gemma":0.002789816,"domain_scores_codex":[0.9995913,0.00004352654,0.00006176069,0.0001280119,0.00007740907,0.00009794816],"domain_scores_gemma":[0.9995638,0.00002486265,0.0001293718,0.00003064084,0.00003063973,0.0002207547],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002448927,0.00007671971,0.000198086,0.00003321987,0.00001014638,0.0001617449,0.00002156981,0.00005247254,0.9986166,0.00012985,0.0000939037,0.0003608343],"study_design_scores_gemma":[0.0002177533,0.001460572,0.0214484,0.00005422215,0.00009315195,0.002023353,0.000194961,0.002614045,0.9669014,0.0002143023,0.004748045,0.00002982718],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9928843,0.0004977716,0.001635213,0.0002679969,0.00008935501,0.00007354455,0.002013931,0.0002588094,0.002279038],"genre_scores_gemma":[0.9802954,0.0005512263,0.002857237,0.0002202725,0.00002539761,0.0002021795,0.00240062,0.000154113,0.01329361],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003914974,"threshold_uncertainty_score":0.01309693,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05019903484114675,"score_gpt":0.289000545190396,"score_spread":0.2388015103492493,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}