{"id":"W2886320592","doi":"10.1158/1538-7445.am2018-1477","title":"Abstract 1477: The interactomes of H3.1 and H3.3 reveal novel interactions, and associations with histone chaperones","year":2018,"lang":"en","type":"article","venue":"Cancer Research","topic":"RNA and protein synthesis mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Princess Margaret Cancer Centre; Hospital for Sick Children","funders":"","keywords":"Histone H3; Chromatin; Histone; Interactome; Biotinylation; Biology; Cell biology; Histone code; Computational biology; Chromodomain; Genetics; Molecular biology; DNA; Gene; Nucleosome; RNA","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000116217,0.0002885778,0.000304118,0.0003632111,0.0002609068,0.0004706122,0.0002723192,0.0004040866,0.009280701],"category_scores_gemma":[0.0001163162,0.0001626364,0.0003711034,0.0004260801,0.0001717354,0.000287662,0.0003816879,0.0006132106,0.003003148],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003877889,"about_ca_system_score_gemma":0.000191235,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008845861,"about_ca_topic_score_gemma":0.0011072,"domain_scores_codex":[0.999845,0.000007945511,0.000007239633,0.00004935281,0.00004636431,0.00004406348],"domain_scores_gemma":[0.9999018,0.00001270609,0.00002195039,0.000007004521,0.0000181172,0.00003845337],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000230801,0.00001398438,0.00209666,0.0000604167,0.00001531253,0.00009211692,0.00001632221,0.00002776457,0.9946044,0.0001138262,0.0004495836,0.002278807],"study_design_scores_gemma":[0.00003505503,0.0002579729,0.1913012,0.00002777676,0.0000772514,0.001744629,0.0001457277,0.002267394,0.7832395,0.0003252274,0.02055855,0.00001981694],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9661542,0.006813881,0.00996738,0.0006843728,0.0001471774,0.00003584014,0.008546383,0.0003980393,0.007252679],"genre_scores_gemma":[0.9654637,0.001642075,0.007112065,0.0003973923,0.00005089353,0.00005636528,0.01102905,0.0001459644,0.01410258],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.009280701,"threshold_uncertainty_score":0.03104705,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05671798711052985,"score_gpt":0.3961180392547726,"score_spread":0.3394000521442427,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}