{"id":"W2886522468","doi":"10.1158/1538-7445.am2018-3673","title":"Abstract 3673: Targeting the epigenome of small cell hypercalcemic carcinoma of the ovary, hypercalcemic type (SCCOHT)","year":2018,"lang":"en","type":"article","venue":"Cancer Research","topic":"Chromatin Remodeling and Cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"","keywords":"SMARCA4; Biology; Epigenome; Cancer research; Chromatin remodeling; EZH2; Chromatin; Epigenetics; Cell cycle checkpoint; Histone; Cell cycle; Cell biology; Cancer; Genetics; DNA methylation; Gene expression","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006873658,0.0002734118,0.000291693,0.0002056373,0.0001239666,0.0001903197,0.0001374216,0.000220952,0.002092625],"category_scores_gemma":[0.00005747462,0.000107795,0.0002056753,0.0002499688,0.0001134445,0.00009034447,0.0001264342,0.000364259,0.0003193314],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002286409,"about_ca_system_score_gemma":0.0003238435,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001142712,"about_ca_topic_score_gemma":0.003215576,"domain_scores_codex":[0.999949,0.000003885035,0.000004252882,0.000009846531,0.00001621926,0.00001675005],"domain_scores_gemma":[0.9999794,0.000002755005,0.000004018104,0.000002586765,0.000003998601,0.000007165962],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0003534745,0.00009806089,0.0006670968,0.0001433399,0.00002367888,0.0001489938,0.00001356569,0.0001775879,0.9882323,0.0001818417,0.0004950384,0.009465073],"study_design_scores_gemma":[0.0001791112,0.001507851,0.0117295,0.00001073213,0.0001021087,0.001045016,0.00003577217,0.0008544667,0.968967,0.00007086193,0.01549019,0.000007369953],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"other","genre_scores_codex":[0.9807884,0.008656768,0.002808694,0.0003304767,0.0001199866,0.0001634966,0.001521821,0.0002610424,0.005349307],"genre_scores_gemma":[0.9890354,0.003115234,0.001621043,0.0001571272,0.00001702025,0.00005931934,0.001362973,0.00001706676,0.004614786],"genre_candidate":"other","genre_consensus":null,"teacher_disagreement_score":0.002092625,"threshold_uncertainty_score":0.007000566,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05717682523361722,"score_gpt":0.3411357614902597,"score_spread":0.2839589362566425,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}