{"id":"W2886577448","doi":"10.15698/cst2018.07.149","title":"GFI1’s role in DNA repair suggests implications for tumour cell response to treatment","year":2018,"lang":"en","type":"letter","venue":"Cell Stress","topic":"Blood disorders and treatments","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; Université de Montréal; Montreal Clinical Research Institute","funders":"Fonds de Recherche du Québec - Santé; Canadian Institutes of Health Research","keywords":"DNA repair; DNA damage; Cancer research; Biology; Leukemia; Chronic lymphocytic leukemia; DNA; Immunotherapy; Transcription factor; Cancer; Immunology; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00007404913,0.0004074936,0.0003130617,0.0001121,0.00009882648,0.00003376982,0.0002858168,0.0006147217,0.0000167685],"category_scores_gemma":[0.0000220448,0.0003803103,0.0002715184,0.00009179303,0.00004189002,0.000002307989,0.0000974109,0.0001304248,0.0000507789],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00008821343,"about_ca_system_score_gemma":0.0001727825,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001430214,"about_ca_topic_score_gemma":0.0003570478,"domain_scores_codex":[0.9981809,0.000100952,0.000278684,0.000847218,0.00008686518,0.0005054302],"domain_scores_gemma":[0.9987917,0.00004986867,0.000120276,0.0008434093,0.00008874576,0.0001060054],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0006395094,0.0009451721,0.003528832,0.000109085,0.0001248383,0.00004110319,0.0001285223,0.00001415547,0.07980724,9.619959e-7,0.9136993,0.0009613358],"study_design_scores_gemma":[0.001584771,0.001280274,0.002273281,0.0000251729,0.00009354446,0.000002726719,0.00003165369,0.000002036237,0.2481627,0.00003995286,0.7461416,0.0003622768],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.916512,0.002858815,0.00005618485,0.07070076,0.0003167931,0.002695437,0.003224652,0.00006473889,0.003570702],"genre_scores_gemma":[0.7914933,0.0006083411,0.002552026,0.103672,0.004132465,0.005008099,0.01586476,0.0004280377,0.07624093],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1683555,"threshold_uncertainty_score":0.9998649,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009524104835891205,"score_gpt":0.2539430518679712,"score_spread":0.24441894703208,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}