{"id":"W2886582879","doi":"10.3390/v10080421","title":"Going (Reo)Viral: Factors Promoting Successful Reoviral Oncolytic Infection","year":2018,"lang":"en","type":"review","venue":"Viruses","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":26,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta; University of Calgary","funders":"Canadian Institutes of Health Research","keywords":"Oncolytic virus; Biology; Viral replication; Virus; Virotherapy; Viral infection; Cancer; Virology; Drug development; Drug; Computational biology; Pharmacology; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0005987928,0.0006474142,0.0009496531,0.0002748145,0.0002514911,0.0001461649,0.0005637303,0.0006733388,0.0001214162],"category_scores_gemma":[0.0003426145,0.0005409171,0.000551739,0.0003658496,0.0001914827,0.00001737564,0.0003550096,0.0004591048,0.0003841922],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001522309,"about_ca_system_score_gemma":0.0006604763,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001136002,"about_ca_topic_score_gemma":0.0002838784,"domain_scores_codex":[0.9968503,0.0005252539,0.0006550057,0.0009289741,0.0003657426,0.0006747318],"domain_scores_gemma":[0.9983258,0.00006965461,0.0004337009,0.0008761752,0.0001215276,0.0001731182],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0003679334,0.0003024319,0.001361642,0.01154225,0.001116727,0.00002425972,0.000103592,0.000003420394,0.01510171,0.00001455311,0.004420515,0.965641],"study_design_scores_gemma":[0.0002027985,0.002277846,0.000009677144,0.001961013,0.0001927131,0.00001596311,0.000003701935,0.000003451098,0.0222997,0.00000964318,0.9724331,0.0005903677],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.07695021,0.9209462,0.00002076574,0.000004072089,0.0004488603,0.0009501358,0.00007706597,0.00008946455,0.0005131971],"genre_scores_gemma":[0.001969461,0.9950759,0.00004213995,0.00009296471,0.001515801,0.0001362949,0.0003631402,0.000204762,0.0005995111],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9680126,"threshold_uncertainty_score":0.9997042,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07632210373332633,"score_gpt":0.3942724946398095,"score_spread":0.3179503909064832,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}