{"id":"W2886582879","doi":"10.3390/v10080421","title":"Going (Reo)Viral: Factors Promoting Successful Reoviral Oncolytic Infection","year":2018,"lang":"en","type":"review","venue":"Viruses","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":26,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta; University of Calgary","funders":"Canadian Institutes of Health Research","keywords":"Oncolytic virus; Biology; Viral replication; Virus; Virotherapy; Viral infection; Cancer; Virology; Drug development; Drug; Computational biology; Pharmacology; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000482132,0.0005939088,0.0004002765,0.0005326016,0.0002339633,0.001088082,0.0002423731,0.0005402142,0.00303214],"category_scores_gemma":[0.0005311235,0.0001934211,0.0004400281,0.000312673,0.0004015894,0.0006788909,0.0003578542,0.000932596,0.001768102],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005564425,"about_ca_system_score_gemma":0.0004470712,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005374859,"about_ca_topic_score_gemma":0.0007682362,"domain_scores_codex":[0.9997504,0.00003814591,0.0000227623,0.00004894506,0.00008420202,0.00005542839],"domain_scores_gemma":[0.999792,0.00007661256,0.0000534009,0.00001392841,0.00003797685,0.00002599177],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0002795676,0.00008109715,0.00103295,0.0025569,0.0000426956,0.0006301079,0.0002209753,0.0004643082,0.8500645,0.01195084,0.005085276,0.1275908],"study_design_scores_gemma":[0.00003054493,0.0003819918,0.004199644,0.0004298537,0.00009973987,0.003311775,0.0001577365,0.0005516939,0.6001194,0.001846725,0.3888088,0.00006209454],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.291512,0.5531921,0.06929779,0.002382368,0.002529034,0.0006335371,0.002897133,0.001728915,0.07582712],"genre_scores_gemma":[0.6492497,0.264325,0.04268694,0.0009705185,0.000741787,0.0002579635,0.003942896,0.0005475628,0.03727766],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.00303214,"threshold_uncertainty_score":0.01014352,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07632210373332633,"score_gpt":0.3942724946398095,"score_spread":0.3179503909064832,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}