{"id":"W2886594625","doi":"10.1113/jp276803","title":"Membrane raft redox signalling contributes to renal tubular cell epithelial–mesenchymal transition and fibrosis and inflammation of the kidneys","year":2018,"lang":"en","type":"letter","venue":"The Journal of Physiology","topic":"Erythrocyte Function and Pathophysiology","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Ted Rogers Centre for Heart Research; McMaster University; University of Toronto","funders":"","keywords":"Cell biology; Epithelial–mesenchymal transition; Sphingomyelin phosphodiesterase; Acid sphingomyelinase; Angiotensin II; Fibrosis; Chemistry; Lipid raft; Biology; Ceramide; Signal transduction; Cancer research; Internal medicine; Biochemistry; Downregulation and upregulation; Medicine; Receptor","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002973138,0.0003541148,0.0004739806,0.0003721985,0.0004207659,0.0006239914,0.0002309104,0.0007211352,0.001510228],"category_scores_gemma":[0.0002065997,0.0002295837,0.0006428926,0.000219413,0.0003244612,0.0005813559,0.0007520234,0.001120745,0.0003492399],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003163751,"about_ca_system_score_gemma":0.0004568761,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005574671,"about_ca_topic_score_gemma":0.0008339761,"domain_scores_codex":[0.9997335,0.00003721805,0.00001883229,0.00005505247,0.00008040118,0.00007490491],"domain_scores_gemma":[0.9998677,0.000007124864,0.00004129952,0.000008409123,0.00003814769,0.00003741502],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.000920273,0.000169491,0.004020251,0.001405825,0.0001410238,0.00102777,0.0003002725,0.0003402798,0.9566804,0.002448049,0.002173496,0.03037285],"study_design_scores_gemma":[0.0003158322,0.001309069,0.1520299,0.0003513099,0.0008433911,0.005880308,0.001300337,0.007321407,0.7146987,0.00686559,0.1089033,0.0001808088],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"other","genre_scores_codex":[0.8617677,0.1114452,0.01232702,0.00474498,0.001065443,0.0001189973,0.0009297779,0.0003257251,0.007275194],"genre_scores_gemma":[0.970802,0.02085056,0.001891756,0.0006463879,0.000192271,0.00006630251,0.0003943076,0.00002468563,0.005131718],"genre_candidate":"other","genre_consensus":null,"teacher_disagreement_score":0.001510228,"threshold_uncertainty_score":0.005052209,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008780174071274016,"score_gpt":0.2187077640552463,"score_spread":0.2099275899839723,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}