{"id":"W2886638978","doi":"10.1111/bjh.15519","title":"Validation of the <scp>MCL</scp>35 gene expression proliferation assay in randomized trials of the European Mantle Cell Lymphoma Network","year":2018,"lang":"en","type":"article","venue":"British Journal of Haematology","topic":"Lymphoma Diagnosis and Treatment","field":"Medicine","cited_by":25,"is_retracted":false,"has_abstract":true,"ca_institutions":"BC Cancer Agency","funders":"National Cancer Institute","keywords":"Mantle cell lymphoma; Medicine; International Prognostic Index; Oncology; Lymphoma; Clinical trial; Internal medicine; Proliferation index; Cancer research; Immunohistochemistry; Diffuse large B-cell lymphoma","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.04088803,0.0005571385,0.001127296,0.0003537251,0.0003078443,0.001015683,0.0004767292,0.0009873512,0.001452572],"category_scores_gemma":[0.03316136,0.000218947,0.001510485,0.0005978976,0.0008553418,0.0008097597,0.0006809533,0.001262014,0.0002858519],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005535368,"about_ca_system_score_gemma":0.0008462758,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001944856,"about_ca_topic_score_gemma":0.0004343723,"domain_scores_codex":[0.9472136,0.04684836,0.002206777,0.001622534,0.001644955,0.0004637762],"domain_scores_gemma":[0.971696,0.01779599,0.006585278,0.002253093,0.001011919,0.0006577516],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.790131,0.001645958,0.09043201,0.002538047,0.01065044,0.00009561021,0.0002240187,0.004308859,0.01172349,0.001961919,0.001820081,0.08446862],"study_design_scores_gemma":[0.2948798,0.268527,0.3579929,0.0008492809,0.01578599,0.0005968221,0.0002082898,0.01466374,0.01818141,0.005781234,0.02232411,0.000209389],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9622604,0.01466479,0.01050496,0.0017218,0.0003971952,0.004662066,0.001853866,0.00009980249,0.003835097],"genre_scores_gemma":[0.9880508,0.0007614223,0.005295013,0.0007883773,0.0001520288,0.003593048,0.0009956879,0.00002002217,0.0003437132],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.04088803,"threshold_uncertainty_score":0.2162392,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02141079604909979,"score_gpt":0.2683324955108397,"score_spread":0.2469216994617399,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}