{"id":"W2886664817","doi":"10.1016/j.ajpath.2018.07.008","title":"Helminth Antigen–Conditioned Dendritic Cells Generate Anti-Inflammatory Cd4 T Cells Independent of Antigen Presentation via Major Histocompatibility Complex Class II","year":2018,"lang":"en","type":"article","venue":"American Journal Of Pathology","topic":"Immunotherapy and Immune Responses","field":"Immunology and Microbiology","cited_by":7,"is_retracted":false,"has_abstract":false,"ca_institutions":"Hotchkiss Brain Institute; University of Calgary","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; Alberta Innovates; University of Calgary","keywords":"Antigen presentation; Immunology; Major histocompatibility complex; Antigen; Antigen-presenting cell; MHC class II; Biology; Dendritic cell; Immune system; T cell","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003138557,0.0007722846,0.0004290103,0.0004201897,0.000229239,0.0005691007,0.0002703863,0.0006693872,0.001827226],"category_scores_gemma":[0.0003136371,0.0002811454,0.0003570142,0.000192532,0.0003780943,0.0003662567,0.0004279418,0.002087707,0.0007278128],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000371492,"about_ca_system_score_gemma":0.0003467576,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002031482,"about_ca_topic_score_gemma":0.0005629822,"domain_scores_codex":[0.9996334,0.00004602391,0.00002706566,0.00007271023,0.00009065458,0.0001300466],"domain_scores_gemma":[0.9996787,0.00007068908,0.00006045607,0.00005020337,0.00004215188,0.00009774872],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003503656,0.00009877917,0.0002352021,0.0000484828,0.000006602971,0.00006719081,0.0000247053,0.00007030759,0.9969406,0.0001452841,0.00008927776,0.001923177],"study_design_scores_gemma":[0.0002255672,0.0006425738,0.002352615,0.00001492427,0.00003718855,0.000167721,0.0000481051,0.001212482,0.9928741,0.0001738891,0.002243011,0.000007787395],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9928973,0.0005207894,0.003025963,0.0001965837,0.0002768821,0.0001365958,0.0004705442,0.0001089362,0.002366364],"genre_scores_gemma":[0.9916006,0.0004050515,0.003342575,0.0001614534,0.000123246,0.00008882615,0.0005544645,0.00004963388,0.003674011],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001827226,"threshold_uncertainty_score":0.006112754,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01233438575862864,"score_gpt":0.2598110031506196,"score_spread":0.247476617391991,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}