{"id":"W2886734994","doi":"10.1016/j.cyto.2018.07.032","title":"Essential role of suppressor of cytokine signaling 1 (SOCS1) in hepatocytes and macrophages in the regulation of liver fibrosis","year":2018,"lang":"en","type":"article","venue":"Cytokine","topic":"Liver physiology and pathology","field":"Medicine","cited_by":30,"is_retracted":false,"has_abstract":false,"ca_institutions":"Université de Sherbrooke","funders":"Fonds de Recherche du Québec - Santé; Canadian Institutes of Health Research; National Institutes of Health","keywords":"Suppressor of cytokine signaling 1; Cytokine; Fibrosis; Cancer research; Hepatocyte; Hepatic fibrosis; Cell biology; Myofibroblast; Chemistry; Biology; Immunology; Medicine; Pathology; Suppressor; Cancer","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002455929,0.00007945543,0.000315396,0.0001171546,0.00001576492,0.000001112552,0.00007555014,0.00009906598,0.0001288248],"category_scores_gemma":[0.0000811483,0.00005762439,0.00003758521,0.0001684828,0.0003885034,0.00004501975,0.00004447509,0.00009059593,0.000001312353],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000006395671,"about_ca_system_score_gemma":0.00002058732,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002951911,"about_ca_topic_score_gemma":0.00004902306,"domain_scores_codex":[0.9992325,0.0001258475,0.000298652,0.0001366401,0.00009634838,0.0001100579],"domain_scores_gemma":[0.9993572,0.0002180653,0.0001455856,0.000179734,0.00008442913,0.00001493962],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0006708363,0.0001209282,0.09194454,0.0001361577,0.00001704539,0.000005714394,0.002339353,0.00001063006,0.9041601,0.0002560959,0.00001847625,0.0003201232],"study_design_scores_gemma":[0.000717856,0.0003524355,0.4108419,0.00009130691,0.00003075302,0.000009837998,0.0001057225,0.0003341823,0.5870736,0.0003990952,0.00001567463,0.00002771635],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9990063,0.0005070014,0.00001601633,0.0000711937,0.00002215042,0.0001944003,0.00002986023,0.000003708325,0.000149387],"genre_scores_gemma":[0.9994146,0.00005575044,0.0003659588,0.00003180929,0.00008841516,0.000005546163,0.00002090377,0.000006335789,0.00001068601],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3188973,"threshold_uncertainty_score":0.2349854,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01139983541401842,"score_gpt":0.2538790820482793,"score_spread":0.2424792466342609,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}