{"id":"W2886812832","doi":"10.1016/j.virusres.2018.08.008","title":"Toll-like receptor (TLR)4 signalling induces myeloid differentiation primary response gene (MYD) 88 independent pathway in avian species leading to type I interferon production and antiviral response","year":2018,"lang":"en","type":"article","venue":"Virus Research","topic":"Immune Response and Inflammation","field":"Immunology and Microbiology","cited_by":18,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Calgary","funders":"Agriculture and Agri-Food Canada; Alberta Livestock and Meat Agency; Canadian Poultry Research Council","keywords":"Biology; TLR4; Interferon; Toll-like receptor; Receptor; Signal transduction; Lipopolysaccharide; Interferon type I; Cell biology; Immunology; Innate immune system; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000108112,0.0001979047,0.0001209618,0.0002378071,0.0002635686,0.0002709952,0.0001411057,0.0002945628,0.001738196],"category_scores_gemma":[0.000080652,0.0002127338,0.0002458427,0.00005650009,0.0002180619,0.0002239214,0.0002453498,0.0005149907,0.0004846675],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002979133,"about_ca_system_score_gemma":0.0001670298,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008001366,"about_ca_topic_score_gemma":0.001872991,"domain_scores_codex":[0.9998945,0.00001335999,0.000007604861,0.0000295989,0.00001628802,0.00003851357],"domain_scores_gemma":[0.9999241,0.00000554603,0.0000270615,0.000005811309,0.00001300432,0.00002451644],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000198023,0.00001229505,0.001898069,0.00004808326,0.000004315526,0.000111002,0.00003272552,0.00003088336,0.9964873,0.00009997577,0.00008104782,0.0009963912],"study_design_scores_gemma":[0.0000687442,0.001083816,0.3931377,0.00007919037,0.00006644097,0.001782202,0.0008213458,0.001747267,0.5931646,0.0004248462,0.007592158,0.00003165964],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.994996,0.001078389,0.001191812,0.0001083441,0.0000418471,0.00002100976,0.0004043941,0.00002980359,0.002128363],"genre_scores_gemma":[0.9926623,0.0004914852,0.001570552,0.00009487091,0.00001343701,0.00002521664,0.0007530467,0.000009391772,0.00437962],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001738196,"threshold_uncertainty_score":0.00581485,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05398403947859807,"score_gpt":0.3129025149781896,"score_spread":0.2589184754995915,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}