{"id":"W2886819625","doi":"10.1016/j.jgo.2018.07.015","title":"The efficacy and toxicity of immune checkpoint inhibitors in a real-world older patient population","year":2018,"lang":"en","type":"article","venue":"Journal of Geriatric Oncology","topic":"Cancer Immunotherapy and Biomarkers","field":"Medicine","cited_by":76,"is_retracted":false,"has_abstract":false,"ca_institutions":"Kingston Health Sciences Centre; Queen's University","funders":"","keywords":"Medicine; Ipilimumab; Nivolumab; Pembrolizumab; Internal medicine; Population; Context (archaeology); Adverse effect; Immunotherapy; Oncology; Lung cancer; Cancer; Renal cell carcinoma","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008819887,0.00007290475,0.0003325563,0.0002284164,0.00004920553,0.000005741986,0.00005211358,0.00007609234,0.00004002327],"category_scores_gemma":[0.0001291104,0.00004461299,0.0001015986,0.0003491948,0.0001237726,0.00004434945,0.00002489461,0.0001603151,5.91637e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002727019,"about_ca_system_score_gemma":0.0001702459,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004237819,"about_ca_topic_score_gemma":0.000357686,"domain_scores_codex":[0.9986058,0.0001098346,0.0009295405,0.00007383856,0.0001534756,0.0001274975],"domain_scores_gemma":[0.9987378,0.0001888155,0.0007853729,0.0001034002,0.0001397579,0.0000448168],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"observational","study_design_scores_codex":[0.02780271,0.001180316,0.1095637,0.00008178335,0.0003027577,0.00007059221,0.003557813,0.000004113025,0.2583207,0.00005353607,0.001997626,0.5970644],"study_design_scores_gemma":[0.005509971,0.00470674,0.9669933,0.0001013424,0.00006619943,0.0001561329,0.0002048608,0.00001418578,0.01494412,0.00006782317,0.00718056,0.00005470614],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9953218,0.001443704,0.000005660131,0.001639291,0.000692954,0.000204503,5.628939e-7,0.000002667896,0.0006888731],"genre_scores_gemma":[0.9981137,0.00109071,0.0002484253,0.00007669622,0.0004050627,0.000001607662,5.837451e-7,0.00000648512,0.00005675038],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.8574297,"threshold_uncertainty_score":0.1819265,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01259739462838549,"score_gpt":0.3136205981020948,"score_spread":0.3010232034737093,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}