{"id":"W2886839127","doi":"10.1136/gutjnl-2018-316702","title":"Responsiveness of histological disease activity indices in ulcerative colitis: a post hoc analysis using data from the TOUCHSTONE randomised controlled trial","year":2018,"lang":"en","type":"article","venue":"Gut","topic":"Inflammatory Bowel Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":62,"is_retracted":false,"has_abstract":true,"ca_institutions":"Robarts Clinical Trials","funders":"Takeda Canada; Celgene; UCB Pharma; Pfizer","keywords":"Medicine; Intraclass correlation; Placebo; Receiver operating characteristic; Internal medicine; Post-hoc analysis; Ulcerative colitis; Physical therapy; Gastroenterology; Disease; Pathology; Psychometrics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.07350014,0.001648623,0.00741739,0.0009825263,0.000498795,0.001925722,0.001178089,0.002068453,0.004823698],"category_scores_gemma":[0.1037833,0.000649954,0.006704418,0.0009703518,0.001638384,0.002388319,0.001608175,0.002733872,0.0004238765],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006191107,"about_ca_system_score_gemma":0.001024566,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000386588,"about_ca_topic_score_gemma":0.000466211,"domain_scores_codex":[0.887942,0.09584642,0.005710752,0.005035028,0.003908094,0.001557722],"domain_scores_gemma":[0.843435,0.1279162,0.01378289,0.01019915,0.003299787,0.001366991],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"observational","study_design_scores_codex":[0.9451368,0.0005936658,0.01280017,0.001978275,0.02371826,0.0001290369,0.0002728438,0.001373191,0.00170958,0.0001625938,0.0005756374,0.01154993],"study_design_scores_gemma":[0.5037279,0.2358047,0.1683845,0.0006974767,0.06452409,0.0003223808,0.0004520538,0.01554372,0.003710814,0.002121116,0.004396535,0.0003148824],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9743485,0.01042318,0.006713435,0.0004749942,0.0009196743,0.004060999,0.001188627,0.0001922537,0.00167836],"genre_scores_gemma":[0.9920655,0.0005739123,0.002084327,0.0003295795,0.0002250317,0.003275418,0.0006231387,0.00005587625,0.0007672014],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.07350014,"threshold_uncertainty_score":0.3887106,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03007532430897776,"score_gpt":0.3132228634167142,"score_spread":0.2831475391077364,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}