{"id":"W2886986327","doi":"10.1212/wnl.90.15_supplement.p3.398","title":"Efficacy and Safety of 2 Doses of Ponesimod (10 and 20 mg o.d.): Interim Analysis of a Phase II Extension Trial in Relapsing-remitting Multiple Sclerosis (P3.398)","year":2018,"lang":"en","type":"article","venue":"Neurology","topic":"Fungal Plant Pathogen Control","field":"Agricultural and Biological Sciences","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Ottawa","funders":"","keywords":"Relapsing remitting; Interim analysis; Medicine; Interim; Multiple sclerosis; Anesthesia; Nuclear medicine; Internal medicine; Clinical trial; Political science; Psychiatry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.003665078,0.001848887,0.002467141,0.0004527337,0.0004946443,0.001036135,0.001009704,0.001932093,0.004409199],"category_scores_gemma":[0.002288723,0.0007653452,0.002036206,0.0003481617,0.0009719112,0.001489758,0.0004590724,0.003646163,0.0009165062],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006208479,"about_ca_system_score_gemma":0.001347462,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007166584,"about_ca_topic_score_gemma":0.001324334,"domain_scores_codex":[0.9991661,0.000435577,0.00005190213,0.0001218924,0.00005728214,0.0001671675],"domain_scores_gemma":[0.9985214,0.0004232077,0.0003652083,0.0001691204,0.00008568788,0.0004353494],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.9672698,0.007823882,0.0008931103,0.000212935,0.0006426048,0.00006630376,0.00006336918,0.0005511991,0.005491413,0.00006642338,0.0005564888,0.01636243],"study_design_scores_gemma":[0.784131,0.2072758,0.005101841,0.00002385696,0.0006812169,0.00008794713,0.00002413788,0.0004791152,0.001456811,0.0001947406,0.0005192371,0.00002442155],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9922642,0.001742995,0.000783752,0.0003429849,0.0001598147,0.001743674,0.001370105,0.0001389472,0.001453546],"genre_scores_gemma":[0.9895572,0.0009878287,0.002127005,0.0005698875,0.0001956119,0.002684657,0.001804515,0.00004412315,0.002029228],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004409199,"threshold_uncertainty_score":0.01938301,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04093059725404592,"score_gpt":0.2550416671672511,"score_spread":0.2141110699132052,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}