{"id":"W2887221513","doi":"10.1038/s41467-018-05771-8","title":"Galectin-9 binds IgM-BCR to regulate B cell signaling","year":2018,"lang":"en","type":"article","venue":"Nature Communications","topic":"Galectins and Cancer Biology","field":"Immunology and Microbiology","cited_by":106,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary; Canada Research Chairs; University of Toronto","funders":"Canadian Institutes of Health Research; Natural Sciences and Engineering Research Council of Canada; Canada Research Chairs; Government of Canada; Universities Space Research Association","keywords":"breakpoint cluster region; CD22; B-cell receptor; Cell biology; B cell; Immune system; Signal transduction; Chemistry; Biology; Cancer research; Immunology; Receptor; Antibody; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000108239,0.0002584304,0.0001587078,0.0001855377,0.0001592168,0.0004284624,0.0002272975,0.0003033697,0.001375854],"category_scores_gemma":[0.00009467454,0.0001414163,0.0002603539,0.0001336857,0.0001831108,0.0002873769,0.000404366,0.0006422554,0.0005537585],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000549772,"about_ca_system_score_gemma":0.0001205683,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003457852,"about_ca_topic_score_gemma":0.0003698011,"domain_scores_codex":[0.9998412,0.00002832467,0.000007312889,0.00002880767,0.0000500277,0.00004424792],"domain_scores_gemma":[0.9999557,0.000006406171,0.00001169588,0.000005008697,0.000007127339,0.00001407841],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0000212039,0.000004404439,0.0001392982,0.00001939523,0.000002817438,0.00002293281,0.00000523684,0.00006272822,0.9986159,0.0001724762,0.00004729432,0.0008863286],"study_design_scores_gemma":[0.000009500404,0.00003808332,0.003191394,0.000005045001,0.000006437043,0.0001790785,0.00001689464,0.001811471,0.9909266,0.0001532432,0.003658206,0.000004149921],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9728523,0.003769295,0.01771162,0.0004754014,0.00005036627,0.00003927148,0.0004989063,0.0002602988,0.004342536],"genre_scores_gemma":[0.9923095,0.0009536244,0.004665004,0.0001408494,0.0000114238,0.00001735998,0.0002500963,0.00001945475,0.001632767],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001375854,"threshold_uncertainty_score":0.004602671,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0154980431662044,"score_gpt":0.2906819748848457,"score_spread":0.2751839317186413,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}