{"id":"W2887258962","doi":"10.1002/mdc3.12673","title":"Imaging Markers of Progression in Parkinson's Disease","year":2018,"lang":"en","type":"review","venue":"Movement Disorders Clinical Practice","topic":"Parkinson's Disease Mechanisms and Treatments","field":"Medicine","cited_by":27,"is_retracted":false,"has_abstract":true,"ca_institutions":"Toronto Western Hospital; University of Toronto; Ontario Brain Institute; Centre for Addiction and Mental Health","funders":"National Institute of Neurological Disorders and Stroke; Medical Research Council; National Institutes of Health; Deutsche Forschungsgemeinschaft; Eli Lilly and Company; National Health and Medical Research Council; European Commission; Parkinson's UK; CHDI Foundation; Michael J. Fox Foundation for Parkinson's Research; Canadian Institutes of Health Research; U.S. Department of Veterans Affairs","keywords":"Parkinson's disease; Neuroimaging; Positron emission tomography; Disease; Medicine; Neuroscience; Neuroprotection; Magnetic resonance imaging; Pet imaging; Pathology; Psychology; Radiology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.001967634,0.0006127861,0.002125228,0.0003079267,0.00007026962,0.00003266571,0.0002758467,0.0002560848,0.000222305],"category_scores_gemma":[0.003650316,0.0004778243,0.001124815,0.0004755482,0.0002348551,0.0002720051,0.0002453702,0.0006618664,0.0001192664],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001998721,"about_ca_system_score_gemma":0.0007948549,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00005031543,"about_ca_topic_score_gemma":0.00001104861,"domain_scores_codex":[0.9946363,0.0008831921,0.002017396,0.00112095,0.0008198603,0.0005222879],"domain_scores_gemma":[0.9953582,0.001347097,0.001612577,0.0009646586,0.0001350767,0.0005824252],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.001446119,0.005752185,0.008671278,0.007470214,0.0006312294,0.0003989156,0.00001006947,9.921562e-8,2.786193e-8,0.00005704066,0.003111573,0.9724513],"study_design_scores_gemma":[0.002559357,0.0005623231,0.004028374,0.01602941,0.004699713,0.000002566506,0.00006188868,0.0000485651,1.256501e-7,0.000603336,0.9710349,0.0003694124],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00007503168,0.99119,0.00007132597,0.0008646239,0.0005899612,0.00290555,0.00007671492,0.00005397724,0.004172787],"genre_scores_gemma":[0.0003940657,0.9947473,0.002311997,0.001407923,0.0001781771,0.0003758359,0.0002594049,0.0001047463,0.000220493],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9720818,"threshold_uncertainty_score":0.9997674,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05705142344389732,"score_gpt":0.4402616049265531,"score_spread":0.3832101814826558,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}