{"id":"W2887258962","doi":"10.1002/mdc3.12673","title":"Imaging Markers of Progression in Parkinson's Disease","year":2018,"lang":"en","type":"review","venue":"Movement Disorders Clinical Practice","topic":"Parkinson's Disease Mechanisms and Treatments","field":"Medicine","cited_by":27,"is_retracted":false,"has_abstract":true,"ca_institutions":"Toronto Western Hospital; University of Toronto; Ontario Brain Institute; Centre for Addiction and Mental Health","funders":"National Institute of Neurological Disorders and Stroke; Medical Research Council; National Institutes of Health; Deutsche Forschungsgemeinschaft; Eli Lilly and Company; National Health and Medical Research Council; European Commission; Parkinson's UK; CHDI Foundation; Michael J. Fox Foundation for Parkinson's Research; Canadian Institutes of Health Research; U.S. Department of Veterans Affairs","keywords":"Parkinson's disease; Neuroimaging; Positron emission tomography; Disease; Medicine; Neuroscience; Neuroprotection; Magnetic resonance imaging; Pet imaging; Pathology; Psychology; Radiology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001027177,0.0007774801,0.001140116,0.003300932,0.0001876122,0.000997926,0.0006983172,0.001109911,0.001825284],"category_scores_gemma":[0.001609611,0.0002133386,0.0006817316,0.002059886,0.0005716995,0.0009186491,0.0005034284,0.001174408,0.0007607591],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005603742,"about_ca_system_score_gemma":0.000860373,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001454958,"about_ca_topic_score_gemma":0.001822679,"domain_scores_codex":[0.9996511,0.00008786145,0.00006676432,0.00006707538,0.0001088003,0.00001846394],"domain_scores_gemma":[0.9992006,0.0004200882,0.0001457287,0.00001498543,0.0001909046,0.00002764025],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.000109847,0.00005866373,0.001179442,0.02439276,0.0002023383,0.0002851881,0.000133286,0.0002555998,0.001113025,0.002805585,0.01408414,0.9553802],"study_design_scores_gemma":[0.0000419193,0.0002952154,0.00924468,0.02645366,0.0009571401,0.007374914,0.0003085892,0.0003940041,0.002120869,0.006746748,0.9459789,0.00008345925],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001180327,0.9990797,0.00009913037,0.0001838854,0.00007246566,0.000003361529,0.00001412487,0.000004111199,0.0004251998],"genre_scores_gemma":[0.002373427,0.9967133,0.0003275244,0.000136056,0.0001750399,0.000008781558,0.00002768987,0.000001200399,0.0002370411],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.003300932,"threshold_uncertainty_score":0.006106138,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05705142344389732,"score_gpt":0.4402616049265531,"score_spread":0.3832101814826558,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}