{"id":"W2887287098","doi":"10.1039/c7ob03178e","title":"Light-responsive bicyclic peptides","year":2018,"lang":"en","type":"article","venue":"Organic & Biomolecular Chemistry","topic":"Photochromic and Fluorescence Chemistry","field":"Materials Science","cited_by":32,"is_retracted":false,"has_abstract":true,"ca_institutions":"Alberta Hospital Edmonton; University of Alberta","funders":"Natural Sciences and Engineering Research Council of Canada; Alberta Glycomics Centre; Alberta Innovates - Health Solutions","keywords":"Bicyclic molecule; Chemistry; Computational biology; Stereochemistry; Combinatorial chemistry; Biology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.0001928842,0.0002964942,0.0002514534,0.00002409939,0.0002121421,0.0001036076,0.000687863,0.0002345266,0.007501374],"category_scores_gemma":[0.000239808,0.0002835958,0.0001103791,0.0003094479,0.0003515329,0.0001024653,0.0002417187,0.0001542973,0.002366032],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001201194,"about_ca_system_score_gemma":0.0002172466,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001148828,"about_ca_topic_score_gemma":0.00000113922,"domain_scores_codex":[0.998123,0.00002754616,0.0003045376,0.0006570518,0.0003370027,0.0005508614],"domain_scores_gemma":[0.9986345,0.00002443065,0.0001343928,0.0008014559,0.0001596155,0.0002455983],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003854953,0.00005518133,0.00003362368,0.00005329153,0.00001323794,0.00007617971,0.0001509584,6.003941e-9,0.9967901,0.000005448306,0.00272677,0.00005666293],"study_design_scores_gemma":[0.0003379135,0.00002936659,0.00004558948,0.00005997406,0.00002502176,0.0001604027,0.0001435314,0.0000104386,0.9946601,0.0001399095,0.004028187,0.0003596132],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9815725,0.0002309063,0.005905838,0.0003306072,0.0001975016,0.0001248512,0.00001965655,0.0002459654,0.01137217],"genre_scores_gemma":[0.9968835,0.00001083433,0.0006416436,0.0003406697,0.0005407481,0.00001665896,0.00001628193,0.000049184,0.00150052],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01531095,"threshold_uncertainty_score":0.9999616,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005769315731171378,"score_gpt":0.2255225674483021,"score_spread":0.2197532517171307,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}