{"id":"W2887319556","doi":"10.1155/2018/4056383","title":"Antidepressant Effects of Probucol on Early-Symptomatic YAC128 Transgenic Mice for Huntington’s Disease","year":2018,"lang":"en","type":"article","venue":"Neural Plasticity","topic":"Genetic Neurodegenerative Diseases","field":"Neuroscience","cited_by":16,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Victoria","funders":"Ciência sem Fronteiras; Conselho Nacional de Desenvolvimento Científico e Tecnológico; Coordenação de Aperfeiçoamento de Pessoal de Nível Superior; Australian Government","keywords":"Antidepressant; Probucol; Transgene; Genetically modified mouse; Disease; Pharmacology; Huntington's disease; Medicine; Neuroscience; Internal medicine; Biology; Genetics; Gene; Cholesterol","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001049701,0.0004509932,0.0004443791,0.0002446505,0.0001262849,0.0001676764,0.0003125505,0.0003621429,0.0009276643],"category_scores_gemma":[0.00009897447,0.0001562735,0.0002382269,0.0001429523,0.0001757773,0.0001915063,0.0001138646,0.0009999146,0.0002282436],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001968596,"about_ca_system_score_gemma":0.0002171683,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001179938,"about_ca_topic_score_gemma":0.00236582,"domain_scores_codex":[0.9999009,0.00001265477,0.00001447473,0.00002362183,0.00002190836,0.0000264609],"domain_scores_gemma":[0.9998698,0.00001257226,0.00003767627,0.00001537529,0.00001825077,0.00004629109],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001518224,0.0004992431,0.0003013874,0.00005599681,0.00001863063,0.00008511154,0.00003523849,0.000074353,0.993226,0.0000405417,0.0001065012,0.004038713],"study_design_scores_gemma":[0.0007613176,0.01401314,0.01854761,0.00003861066,0.000128658,0.0003831902,0.00009178007,0.002014376,0.9614592,0.0001013693,0.002435173,0.0000256188],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9976944,0.0007625583,0.0003035731,0.0000824098,0.00004123696,0.00002490758,0.0005895194,0.00005743499,0.0004438595],"genre_scores_gemma":[0.9942834,0.001096554,0.0008395616,0.00007305937,0.00001770622,0.00007733655,0.0009948475,0.00001604314,0.002601428],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001179938,"threshold_uncertainty_score":0.003103316,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02227213731930989,"score_gpt":0.267413437745442,"score_spread":0.2451413004261321,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}