{"id":"W2887359485","doi":"10.1158/1538-7445.am2018-ct168","title":"Abstract CT168: Phase I/II study of dianhydrogalactitol (VAL-083) with radiation therapy in patients with newly diagnosed glioblastoma, MGMT-unmethylated","year":2018,"lang":"en","type":"article","venue":"Cancer Research","topic":"Glioma Diagnosis and Treatment","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Delmar (Canada)","funders":"","keywords":"Temozolomide; Medicine; Bevacizumab; Cancer research; Radiation therapy; Oncology; Radiosensitizer; Cancer; Internal medicine; DNA repair; Chemotherapy; Biology; DNA","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008858593,0.001578005,0.001596816,0.0005222149,0.0003805221,0.0008255171,0.0009100158,0.00108471,0.003822609],"category_scores_gemma":[0.0004973583,0.0006253151,0.001090344,0.0005251294,0.0009805968,0.000602206,0.000344038,0.002815685,0.001044174],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001123458,"about_ca_system_score_gemma":0.001889463,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002306445,"about_ca_topic_score_gemma":0.005737954,"domain_scores_codex":[0.9997039,0.0001324589,0.00001453969,0.00005571028,0.00002768399,0.00006562523],"domain_scores_gemma":[0.9996456,0.0000262879,0.00004881114,0.00003070233,0.00002535752,0.0002232016],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.6186865,0.097789,0.008677461,0.001297389,0.001593128,0.0004522551,0.0004997231,0.003455445,0.1468561,0.0005112732,0.005449094,0.1147326],"study_design_scores_gemma":[0.2405836,0.7345248,0.01057361,0.00005186166,0.0004293525,0.0003587452,0.00009823123,0.0008122333,0.008646633,0.0001845503,0.003703651,0.00003261026],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9928804,0.001737447,0.0003615483,0.0003686757,0.0001329092,0.00210103,0.001024885,0.00009589281,0.001297267],"genre_scores_gemma":[0.9870913,0.002081607,0.001565829,0.0006873275,0.0001345342,0.002615748,0.002408494,0.00003979409,0.003375396],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003822609,"threshold_uncertainty_score":0.01278788,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0366241965840547,"score_gpt":0.3865486394441334,"score_spread":0.3499244428600787,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}