{"id":"W2887377336","doi":"10.1158/1538-7445.am2018-3515","title":"Abstract 3515: Down the rabbit hole with structural effects of FK866 in primary CLL B cells","year":2018,"lang":"en","type":"article","venue":"Cancer Research","topic":"Biochemical and Molecular Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Saint-Boniface; University of Manitoba","funders":"","keywords":"Biology; NAD+ kinase; Chlorambucil; Phalloidin; Cell biology; Nicotinamide phosphoribosyltransferase; Bendamustine; Cancer research; Molecular biology; Cytoskeleton; Cell; Biochemistry; Enzyme; Chronic lymphocytic leukemia; Immunology; Leukemia; Chemotherapy; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001357374,0.0002718211,0.000339301,0.0002029407,0.0002899604,0.0002648593,0.0002349138,0.0004387119,0.004137998],"category_scores_gemma":[0.00008096856,0.0001555344,0.0003957725,0.0001918148,0.0002076727,0.0001799252,0.0002350728,0.0006530751,0.001672999],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003830286,"about_ca_system_score_gemma":0.0001901464,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002403822,"about_ca_topic_score_gemma":0.001974818,"domain_scores_codex":[0.9997769,0.00003037213,0.0000223168,0.00004585827,0.00005275139,0.00007181904],"domain_scores_gemma":[0.9999131,0.00001742869,0.00001511105,0.00001532942,0.00001281272,0.00002623604],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001579158,0.0000510228,0.0000778413,0.00004659758,0.000003325071,0.00006994858,0.00002252512,0.00003304143,0.9986371,0.00006009845,0.00009775253,0.0007426861],"study_design_scores_gemma":[0.0000369724,0.0008594362,0.003701485,0.000007610661,0.00001303661,0.000313445,0.00004046722,0.0003439829,0.9908438,0.00002677328,0.003809347,0.000003806051],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9875072,0.003352536,0.002503559,0.0002713603,0.0001288085,0.00007015327,0.001418386,0.0001793541,0.004568591],"genre_scores_gemma":[0.990178,0.0007513702,0.001721617,0.0001299044,0.00001713129,0.00006996126,0.001154309,0.00002915104,0.0059485],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004137998,"threshold_uncertainty_score":0.01384294,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01521171862019545,"score_gpt":0.3342167614600169,"score_spread":0.3190050428398215,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}