{"id":"W2887378730","doi":"10.3390/cells7080093","title":"The Role of Extracellular Vesicles in Cancer: Cargo, Function, and Therapeutic Implications","year":2018,"lang":"en","type":"review","venue":"Cells","topic":"Extracellular vesicles in disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":106,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"","keywords":"Crosstalk; Cell biology; Tumor microenvironment; Microvesicles; Extracellular vesicles; Carcinogenesis; Context (archaeology); Cancer cell; Function (biology); Immune system; Biology; Metastasis; Chemistry; Cancer; microRNA; Gene; Immunology; Biochemistry; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003695537,0.000469612,0.0007018286,0.001398635,0.0002839759,0.0009529155,0.0004667119,0.001127264,0.001955911],"category_scores_gemma":[0.0005782651,0.0001497655,0.0003162924,0.001270665,0.000468418,0.001353088,0.0007385939,0.001411433,0.0008244774],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005062727,"about_ca_system_score_gemma":0.0008194482,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005518961,"about_ca_topic_score_gemma":0.0007605546,"domain_scores_codex":[0.999886,0.00001935116,0.00001726175,0.00001915591,0.00004167906,0.00001638664],"domain_scores_gemma":[0.9997889,0.0001045659,0.00002422292,0.000006906757,0.00005064557,0.00002474858],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00006822243,0.00005152401,0.0002890198,0.01068502,0.00004869364,0.0003665037,0.0001096716,0.0004963389,0.003542185,0.01207155,0.02281558,0.9494557],"study_design_scores_gemma":[0.000006425424,0.00007551051,0.0005923605,0.002447383,0.00005141131,0.002430934,0.00008214901,0.0001072529,0.001056558,0.003887764,0.9892455,0.00001670264],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.000135216,0.9987357,0.0001131232,0.0003020949,0.0001480153,0.000001502519,0.000008711196,0.000003575112,0.000552062],"genre_scores_gemma":[0.001026561,0.9982367,0.0001090417,0.0001365759,0.0001462274,0.000002845048,0.00001258682,9.610159e-7,0.0003285118],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.001955911,"threshold_uncertainty_score":0.0065431,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01864644609110359,"score_gpt":0.2934780229487268,"score_spread":0.2748315768576232,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}