{"id":"W2887378730","doi":"10.3390/cells7080093","title":"The Role of Extracellular Vesicles in Cancer: Cargo, Function, and Therapeutic Implications","year":2018,"lang":"en","type":"review","venue":"Cells","topic":"Extracellular vesicles in disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":106,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"","keywords":"Crosstalk; Cell biology; Tumor microenvironment; Microvesicles; Extracellular vesicles; Carcinogenesis; Context (archaeology); Cancer cell; Function (biology); Immune system; Biology; Metastasis; Chemistry; Cancer; microRNA; Gene; Immunology; Biochemistry; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002171275,0.0002206866,0.0003469193,0.00004090991,0.00008953237,0.00002261451,0.0003290249,0.0002332149,0.00001165188],"category_scores_gemma":[0.00001649687,0.0001647897,0.0001676675,0.0001262483,0.0002611974,0.000001625942,0.0001116394,0.0001193775,0.000009483844],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002090431,"about_ca_system_score_gemma":0.0002130523,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001771304,"about_ca_topic_score_gemma":0.00003652543,"domain_scores_codex":[0.9988023,0.0001390393,0.0003996978,0.000372104,0.00007659787,0.0002102824],"domain_scores_gemma":[0.998908,0.00005030748,0.000250594,0.0006644894,0.00006182968,0.00006477399],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00001210088,0.00006571398,0.0001209202,0.0009603321,0.0001347493,4.728893e-7,0.00001675236,0.000001395711,0.05509542,0.0004537644,0.0003892889,0.9427491],"study_design_scores_gemma":[0.00008762,0.00004925427,0.00006059534,0.0003865894,0.0002523547,0.000002679586,0.00002370427,0.000003217188,0.008609892,0.000803481,0.989549,0.0001716137],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.001351341,0.9977397,0.00003710891,0.00001149722,0.0001173937,0.0004463513,0.0000644202,0.000005321219,0.0002268075],"genre_scores_gemma":[0.00645029,0.9925926,0.0000291139,0.00001365781,0.0001903138,0.000152798,0.00005773085,0.00004323516,0.0004702688],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9891597,"threshold_uncertainty_score":0.671993,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01864644609110359,"score_gpt":0.2934780229487268,"score_spread":0.2748315768576232,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}