{"id":"W2887408368","doi":"10.1002/smll.201801942","title":"Multiresponsive Supramolecular Theranostic Nanoplatform Based on Pillar[5]arene and Diphenylboronic Acid Derivatives for Integrated Glucose Sensing and Insulin Delivery","year":2018,"lang":"en","type":"article","venue":"Small","topic":"Supramolecular Self-Assembly in Materials","field":"Materials Science","cited_by":79,"is_retracted":false,"has_abstract":true,"ca_institutions":"Ministry of Education and Child Care","funders":"National Natural Science Foundation of China; Alexander von Humboldt-Stiftung","keywords":"Supramolecular chemistry; Nanocarriers; Insulin delivery; Glucose oxidase; Insulin; Gluconic acid; Chemistry; Pillar; Nanotechnology; Drug delivery; Combinatorial chemistry; Materials science; Diabetes mellitus; Biochemistry; Type 1 diabetes; Internal medicine; Endocrinology; Organic chemistry; Biology; Medicine; Molecule; Biosensor","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0006554514,0.000393376,0.0004172146,0.000160395,0.0003283727,0.0002914932,0.0002030237,0.0001895476,0.00006843179],"category_scores_gemma":[0.001271856,0.000340107,0.00005852335,0.0001731398,0.0003752423,0.0001597489,0.0001252343,0.0000958798,0.00003420799],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00008190529,"about_ca_system_score_gemma":0.0001850842,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001376985,"about_ca_topic_score_gemma":0.0001627126,"domain_scores_codex":[0.9978803,0.0002926563,0.0003817158,0.0006861662,0.0002221468,0.0005370579],"domain_scores_gemma":[0.9981788,0.0006769521,0.0001770069,0.0004400313,0.0003762565,0.0001509739],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001209516,0.00005010554,0.00005556518,0.00005779919,0.00002634301,0.0000306339,0.0006373197,0.00001797273,0.9927825,0.0001079631,0.00001803805,0.005006182],"study_design_scores_gemma":[0.002008152,0.00106959,0.001002107,0.0001801865,0.00005913431,0.00002290473,0.0003312453,0.008351703,0.9855624,0.0005976055,0.0003957018,0.000419305],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9806694,0.0006870614,0.01696561,0.0001272414,0.0004319742,0.0008300582,0.00008936177,0.0001426511,0.00005668785],"genre_scores_gemma":[0.9684245,0.0000579079,0.03039676,0.000873002,0.0001006005,0.00003190235,0.00003663651,0.00006996851,0.000008747821],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01343115,"threshold_uncertainty_score":0.9999051,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01579495529252513,"score_gpt":0.2430271552570721,"score_spread":0.227232199964547,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}