{"id":"W2887514019","doi":"10.1016/j.bbcan.2018.07.004","title":"Peroxisomes and cancer: The role of a metabolic specialist in a disease of aberrant metabolism","year":2018,"lang":"en","type":"review","venue":"Biochimica et Biophysica Acta (BBA) - Reviews on Cancer","topic":"Peroxisome Proliferator-Activated Receptors","field":"Biochemistry, Genetics and Molecular Biology","cited_by":96,"is_retracted":false,"has_abstract":false,"ca_institutions":"Montreal Children's Hospital; Jewish General Hospital; McGill University","funders":"Canadian Institutes of Health Research","keywords":"Peroxisome; Biology; Biogenesis; Autophagy; Carcinogenesis; Organelle; Cell biology; Immune system; Biochemistry; Cancer; Gene; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0004897685,0.0009416928,0.003132326,0.0002324813,0.00008068718,0.00004029391,0.0009192392,0.0003901671,0.00007093073],"category_scores_gemma":[0.0001560085,0.0005912397,0.001045978,0.0007007775,0.0006371535,0.00001685774,0.0003429074,0.00045493,0.000009382235],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005378968,"about_ca_system_score_gemma":0.0008588602,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002893031,"about_ca_topic_score_gemma":0.00008537694,"domain_scores_codex":[0.9958107,0.0008451962,0.001386778,0.0010891,0.0003727772,0.0004953778],"domain_scores_gemma":[0.9967461,0.00005309056,0.001594331,0.001242634,0.0001414193,0.0002224253],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0004142895,0.0007812978,0.00002190149,0.01419484,0.001790173,0.000001663505,0.0004259131,7.905886e-7,0.2979791,0.0003589504,0.002261122,0.6817699],"study_design_scores_gemma":[0.0002904266,0.00007555394,0.0001226977,0.006663395,0.001046524,0.000001721019,0.00001124931,0.000001376921,0.1532314,0.00002203705,0.8380107,0.0005229897],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.08380619,0.9124411,2.818827e-7,0.0001832365,0.0003278592,0.001851847,0.00129985,0.000008552207,0.00008101575],"genre_scores_gemma":[0.009126411,0.9878329,0.00003830233,0.0002292772,0.001068765,0.001334598,0.0001620353,0.00011737,0.00009035806],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.8357495,"threshold_uncertainty_score":0.9996539,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02882984707905778,"score_gpt":0.3322956068714645,"score_spread":0.3034657597924067,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}