{"id":"W2887598813","doi":"10.1158/1538-7445.am2018-2930","title":"Abstract 2930: Synergistic and additive anti-tumor effects of MIV-818 in combination with sorafenib in nonclinical hepatocellular carcinoma models","year":2018,"lang":"en","type":"article","venue":"Cancer Research","topic":"Cancer, Hypoxia, and Metabolism","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Spinal Cord Injury BC; BC Cancer Agency","funders":"","keywords":"Sorafenib; Hepatocellular carcinoma; Pharmacology; Medicine; In vivo; Cancer research; Cell growth; Chemistry; Biology; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002440435,0.0005585321,0.0007056789,0.0004482592,0.0001724247,0.0003020508,0.000284455,0.0003150813,0.002820001],"category_scores_gemma":[0.0001284103,0.0001621331,0.0002899441,0.0002736416,0.0002639035,0.0002264428,0.000173145,0.0008082519,0.0005432402],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003196537,"about_ca_system_score_gemma":0.0004950329,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009054133,"about_ca_topic_score_gemma":0.001418613,"domain_scores_codex":[0.9998097,0.00004568843,0.00001673471,0.00002521091,0.00006281333,0.00003994608],"domain_scores_gemma":[0.9998864,0.0000214153,0.00002192794,0.00001206764,0.00001486154,0.00004326653],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.003417859,0.001186839,0.0002573674,0.0001632058,0.00003283419,0.0001448027,0.00004415543,0.000490775,0.9852894,0.0001229373,0.0005584513,0.008291367],"study_design_scores_gemma":[0.0005152673,0.01129182,0.003278209,0.000008593856,0.00006303626,0.000417721,0.00004090175,0.002324203,0.9791369,0.00005852974,0.002851136,0.00001369538],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9927728,0.001517228,0.001410989,0.0001625285,0.00009306333,0.0001471351,0.0005643223,0.0002390396,0.003093002],"genre_scores_gemma":[0.9944866,0.000640105,0.001217146,0.00003883646,0.0000198662,0.00009256134,0.0005984936,0.00001995558,0.002886345],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002820001,"threshold_uncertainty_score":0.009433866,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03460536473925656,"score_gpt":0.3410718426205555,"score_spread":0.3064664778812989,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}