{"id":"W2887662833","doi":"10.1111/apt.14858","title":"Editorial: biologic therapies for primary sclerosing cholangitis—more disappointment than promise?","year":2018,"lang":"en","type":"editorial","venue":"Alimentary Pharmacology & Therapeutics","topic":"Liver Diseases and Immunity","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"Robarts Clinical Trials; University of Calgary","funders":"","keywords":"Medicine; Primary sclerosing cholangitis; Disappointment; Ursodeoxycholic acid; Internal medicine; Gastroenterology; Disease","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.005765416,0.004277977,0.003432674,0.003256391,0.002995757,0.005369621,0.003685765,0.01066431,0.02211738],"category_scores_gemma":[0.02075572,0.001054822,0.002588138,0.001072085,0.001951703,0.003845642,0.000932887,0.01511852,0.01769392],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.002554999,"about_ca_system_score_gemma":0.002354258,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007943356,"about_ca_topic_score_gemma":0.002291149,"domain_scores_codex":[0.9959564,0.0006285462,0.0005091341,0.0004814474,0.002128248,0.0002962349],"domain_scores_gemma":[0.9856974,0.00492744,0.0008998576,0.000363411,0.005786004,0.002325949],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00005754167,0.00001990435,0.0000283792,0.0001649035,0.00001929503,0.0001517877,0.000009550867,0.00003263378,0.00005986105,0.0001906872,0.9950678,0.004197572],"study_design_scores_gemma":[0.0001591676,0.00009016102,0.0004091304,0.0005549629,0.0001014008,0.0007507928,0.00005508526,0.0003016716,0.0003005978,0.001260512,0.9959826,0.00003388601],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"editorial","genre_gemma":"editorial","genre_scores_codex":[0.0000493799,0.002400519,0.0001218728,0.0214905,0.9743648,0.00002113607,0.00004792376,0.00007858368,0.001425242],"genre_scores_gemma":[0.000525521,0.002693376,0.00009212078,0.01618973,0.9721529,0.00001861681,0.00003480461,0.0000399148,0.008253154],"genre_candidate":"editorial","genre_consensus":"editorial","teacher_disagreement_score":0.02211738,"threshold_uncertainty_score":0.07398999,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03111912584977598,"score_gpt":0.3457905388324323,"score_spread":0.3146714129826563,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}