{"id":"W2887751148","doi":"10.1371/journal.ppat.1007224","title":"Molecular basis for CesT recognition of type III secretion effectors in enteropathogenic Escherichia coli","year":2018,"lang":"en","type":"article","venue":"PLoS Pathogens","topic":"Escherichia coli research studies","field":"Biochemistry, Genetics and Molecular Biology","cited_by":20,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University","funders":"Canadian Institutes of Health Research; Natural Sciences and Engineering Research Council of Canada; Canada Research Chairs","keywords":"Enteropathogenic Escherichia coli; Effector; Secretion; Escherichia coli; Microbiology; Chemistry; Biology; Cell biology; Biochemistry; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007081024,0.0002930203,0.0002174163,0.0001380658,0.0001867995,0.0002587154,0.0002537777,0.0004586892,0.0005551722],"category_scores_gemma":[0.0001935122,0.0001376368,0.0004444147,0.0001076899,0.0002463709,0.00017515,0.0002107327,0.000387971,0.0004879178],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004282929,"about_ca_system_score_gemma":0.0002290821,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007205622,"about_ca_topic_score_gemma":0.0004967544,"domain_scores_codex":[0.9999292,0.00001219097,0.000006335181,0.00001505025,0.00002010601,0.00001713524],"domain_scores_gemma":[0.9998896,0.00001467049,0.00003527254,0.00001035601,0.00001751559,0.00003257795],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001560659,0.0000392929,0.001024958,0.00003642837,0.00000755722,0.0004789088,0.0000297795,0.000529615,0.996561,0.0003462159,0.00004413566,0.0007459433],"study_design_scores_gemma":[0.00007977731,0.0004374076,0.05018157,0.00002743486,0.00004221799,0.001848529,0.0001819069,0.01525767,0.9285964,0.0004965719,0.002813841,0.00003666036],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.997221,0.0001785747,0.001894201,0.00006736975,0.000009731661,0.00001571485,0.0000690806,0.00003486767,0.0005094787],"genre_scores_gemma":[0.9971638,0.0001012628,0.001883889,0.00006747044,0.000004813278,0.00001042897,0.0002886451,0.000006597676,0.0004731087],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007205622,"threshold_uncertainty_score":0.003107488,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02248222510007618,"score_gpt":0.2744117604089584,"score_spread":0.2519295353088822,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}