{"id":"W2887751148","doi":"10.1371/journal.ppat.1007224","title":"Molecular basis for CesT recognition of type III secretion effectors in enteropathogenic Escherichia coli","year":2018,"lang":"en","type":"article","venue":"PLoS Pathogens","topic":"Escherichia coli research studies","field":"Biochemistry, Genetics and Molecular Biology","cited_by":20,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University","funders":"Canadian Institutes of Health Research; Natural Sciences and Engineering Research Council of Canada; Canada Research Chairs","keywords":"Enteropathogenic Escherichia coli; Effector; Secretion; Escherichia coli; Microbiology; Chemistry; Biology; Cell biology; Biochemistry; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003112508,0.0001685999,0.0002274949,0.00008446109,0.00006359057,0.00001037806,0.0001466438,0.0001456429,0.00002310387],"category_scores_gemma":[0.0007229183,0.0001703709,0.0001116493,0.0002654002,0.0001361642,0.000005173698,0.0001130699,0.00007872231,0.00001089378],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003176755,"about_ca_system_score_gemma":0.00008060372,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001611057,"about_ca_topic_score_gemma":0.00009901418,"domain_scores_codex":[0.9987312,0.0001594053,0.0002576427,0.0003704034,0.0001670224,0.0003143108],"domain_scores_gemma":[0.9991224,0.00004199526,0.0001033526,0.0002743482,0.0003882533,0.00006965878],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000380989,0.000158661,0.006276165,0.00009105487,0.00008486021,0.000003444097,0.0001046229,0.000003811148,0.9921278,0.000009005826,0.00007673364,0.0006828991],"study_design_scores_gemma":[0.0008750675,0.001865328,0.007881789,0.00008029945,0.00005968039,0.000001446897,0.0000912481,0.0006519074,0.987552,0.00005571084,0.0006648654,0.0002206923],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9975255,0.0003366999,0.0007729505,0.00003182774,0.0001222516,0.0006847135,0.0001135521,0.00001319574,0.0003993834],"genre_scores_gemma":[0.9971689,0.0002034287,0.001911852,0.00008663675,0.0001777934,0.0001931372,0.0001834222,0.00003492835,0.00003990809],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004575789,"threshold_uncertainty_score":0.6947522,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02248222510007618,"score_gpt":0.2744117604089584,"score_spread":0.2519295353088822,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}