{"id":"W2887778922","doi":"10.3390/molecules23081890","title":"Effect of Dendrimer Generation and Aglyconic Linkers on the Binding Properties of Mannosylated Dendrimers Prepared by a Combined Convergent and Onion Peel Approach","year":2018,"lang":"en","type":"article","venue":"Molecules","topic":"Glycosylation and Glycoproteins Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":23,"is_retracted":false,"has_abstract":true,"ca_institutions":"BioPhage Pharma (Canada); Université du Québec à Montréal","funders":"","keywords":"Dendrimer; Chemistry; Click chemistry; Lectin; Adhesion; Biofilm; Glycoprotein; Binding affinities; Receptor; Biochemistry; Combinatorial chemistry; Biophysics; Stereochemistry; Bacteria; Organic chemistry; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002863302,0.0001243014,0.0001371855,0.0000523608,0.0000929341,0.00001889979,0.00008578831,0.00009556364,0.000009575078],"category_scores_gemma":[0.0001390443,0.00008275091,0.0000361611,0.00007738321,0.0002877523,0.000004029695,0.00007296562,0.00005958316,0.00000199114],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000007634812,"about_ca_system_score_gemma":0.00003234885,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003995842,"about_ca_topic_score_gemma":0.000005956595,"domain_scores_codex":[0.999072,0.0002146411,0.0001710598,0.0002422727,0.0001615548,0.0001385024],"domain_scores_gemma":[0.999557,0.00001412696,0.00008769376,0.0001920941,0.0000954631,0.00005357945],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000451441,0.00003684085,0.0006020468,0.00006235913,0.00007332001,2.411925e-7,0.0001106718,0.00001108931,0.9972104,0.00005874801,0.0007075277,0.0006752603],"study_design_scores_gemma":[0.0007301579,0.0015502,0.0001448581,0.0000262953,0.00001961259,0.000003389713,0.00005079505,0.005599864,0.9913765,0.000001611674,0.0004104375,0.00008625376],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9981468,0.0007431675,0.0002016555,0.00009072039,0.00003078932,0.0005184972,0.00001134658,0.000005436301,0.0002515835],"genre_scores_gemma":[0.9993783,0.0001109065,0.00008061186,0.00003550678,0.00002183707,0.00003606326,0.0000775994,0.00001381035,0.0002453289],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005833929,"threshold_uncertainty_score":0.3374484,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01594037501779729,"score_gpt":0.2510014811500323,"score_spread":0.235061106132235,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}