{"id":"W2887778922","doi":"10.3390/molecules23081890","title":"Effect of Dendrimer Generation and Aglyconic Linkers on the Binding Properties of Mannosylated Dendrimers Prepared by a Combined Convergent and Onion Peel Approach","year":2018,"lang":"en","type":"article","venue":"Molecules","topic":"Glycosylation and Glycoproteins Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":23,"is_retracted":false,"has_abstract":true,"ca_institutions":"BioPhage Pharma (Canada); Université du Québec à Montréal","funders":"","keywords":"Dendrimer; Chemistry; Click chemistry; Lectin; Adhesion; Biofilm; Glycoprotein; Binding affinities; Receptor; Biochemistry; Combinatorial chemistry; Biophysics; Stereochemistry; Bacteria; Organic chemistry; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001942889,0.0004562622,0.0001539289,0.0001300031,0.00008169598,0.0001826248,0.00016104,0.0002443243,0.0008847125],"category_scores_gemma":[0.0003939474,0.0001288869,0.0001009267,0.0001462225,0.0001307001,0.0002165375,0.0001386991,0.0002207193,0.0001961557],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002524384,"about_ca_system_score_gemma":0.0001328742,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004778195,"about_ca_topic_score_gemma":0.0006719115,"domain_scores_codex":[0.9999065,0.00001523993,0.000006738527,0.00002238258,0.00001790842,0.00003117162],"domain_scores_gemma":[0.9998016,0.00006539041,0.00006403172,0.0000103695,0.00002526934,0.00003338838],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001713712,0.00002150202,0.00006558977,0.00002449609,0.000004736007,0.00002937314,0.00001441891,0.0001721973,0.9983656,0.00005286101,0.0000217543,0.001056106],"study_design_scores_gemma":[0.000007060202,0.0001226745,0.0004632635,0.000002205472,0.000006956175,0.00002072718,0.000004047341,0.0003962205,0.9986634,0.000007238895,0.0003031478,0.000003048989],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9979907,0.0003564836,0.000822018,0.00001937041,0.000008498085,0.00001200206,0.00003857836,0.00002325594,0.0007290593],"genre_scores_gemma":[0.9975051,0.0003931503,0.0009490445,0.00003027735,0.00000425601,0.00001867275,0.00007158611,0.00001773458,0.001010205],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008847125,"threshold_uncertainty_score":0.002959669,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01594037501779729,"score_gpt":0.2510014811500323,"score_spread":0.235061106132235,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}