{"id":"W2887825290","doi":"10.1161/atvbaha.118.311394","title":"Caveolae Link Ca <sub>V</sub> 3.2 Channels to BK <sub>Ca</sub> -Mediated Feedback in Vascular Smooth Muscle","year":2018,"lang":"en","type":"article","venue":"Arteriosclerosis Thrombosis and Vascular Biology","topic":"Caveolin-1 and cellular processes","field":"Biochemistry, Genetics and Molecular Biology","cited_by":25,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University; Libin Cardiovascular Institute of Alberta; University of Calgary","funders":"Canadian Institutes of Health Research","keywords":"Caveolae; Ryanodine receptor; Vascular smooth muscle; Caveolin; Cell biology; TRPC1; Myocyte; Ion channel; Caveolin 3; Intracellular; Biophysics; Transient receptor potential channel; Caveolin 1; Colocalization; Mesenteric arteries; Chemistry; Biology; Internal medicine; Receptor; Endocrinology; Signal transduction; Medicine; Biochemistry; Artery; Smooth muscle","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001819404,0.0002517917,0.000181443,0.0001839455,0.0002353262,0.0003786253,0.0002482575,0.0003804397,0.0008257893],"category_scores_gemma":[0.0002410755,0.0002361973,0.0002567125,0.00009623704,0.0003001049,0.0005101716,0.0003068937,0.0004414865,0.0002576338],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003612854,"about_ca_system_score_gemma":0.0002478671,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001226078,"about_ca_topic_score_gemma":0.001271054,"domain_scores_codex":[0.9998984,0.00001147808,0.000006192977,0.00002311964,0.00002471422,0.00003608261],"domain_scores_gemma":[0.9997999,0.00003756672,0.00007811333,0.00001314535,0.00003072502,0.00004055374],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001174803,0.000007643875,0.0005169275,0.00002613025,0.00000359813,0.00008487268,0.00001957689,0.00003912162,0.9985048,0.000195828,0.00001867313,0.0004654468],"study_design_scores_gemma":[0.00005282075,0.000305321,0.03043465,0.0000236284,0.00005994675,0.0007853418,0.0001344018,0.00363192,0.9615289,0.0004664645,0.002563848,0.00001279335],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9941463,0.001266781,0.003675128,0.0001019575,0.00002616843,0.00001474024,0.00006641028,0.00005278743,0.0006496238],"genre_scores_gemma":[0.9969057,0.0004276658,0.001661173,0.00005910538,0.00001251315,0.00001287461,0.00005775096,0.00001002888,0.0008530995],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001226078,"threshold_uncertainty_score":0.002762556,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01542146579656227,"score_gpt":0.2417422247301616,"score_spread":0.2263207589335993,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}