{"id":"W2887825290","doi":"10.1161/atvbaha.118.311394","title":"Caveolae Link Ca <sub>V</sub> 3.2 Channels to BK <sub>Ca</sub> -Mediated Feedback in Vascular Smooth Muscle","year":2018,"lang":"en","type":"article","venue":"Arteriosclerosis Thrombosis and Vascular Biology","topic":"Caveolin-1 and cellular processes","field":"Biochemistry, Genetics and Molecular Biology","cited_by":25,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University; Libin Cardiovascular Institute of Alberta; University of Calgary","funders":"Canadian Institutes of Health Research","keywords":"Caveolae; Ryanodine receptor; Vascular smooth muscle; Caveolin; Cell biology; TRPC1; Myocyte; Ion channel; Caveolin 3; Intracellular; Biophysics; Transient receptor potential channel; Caveolin 1; Colocalization; Mesenteric arteries; Chemistry; Biology; Internal medicine; Receptor; Endocrinology; Signal transduction; Medicine; Biochemistry; Artery; Smooth muscle","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0007274845,0.0007033475,0.0008672288,0.0002762768,0.0003395735,0.0001299913,0.0005070886,0.0008158175,0.00006510779],"category_scores_gemma":[0.0001798797,0.0006860312,0.0004151047,0.0005758206,0.0005316542,0.00003179284,0.0005363319,0.0002953215,0.0002969115],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005464679,"about_ca_system_score_gemma":0.0001288744,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00019793,"about_ca_topic_score_gemma":0.001051286,"domain_scores_codex":[0.9959698,0.0003020574,0.0007470592,0.001553207,0.0002565302,0.001171337],"domain_scores_gemma":[0.997973,0.0000472955,0.0001952473,0.001025865,0.0003006654,0.0004579641],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00001804514,0.000200541,0.00569159,0.0000595229,0.0002439912,6.074503e-7,0.0003219364,0.00001175062,0.9888604,0.00002275883,0.0008445268,0.003724315],"study_design_scores_gemma":[0.002138738,0.001432598,0.3867418,0.0001386219,0.0001361583,0.000001755527,0.0001751721,0.0001574281,0.5740937,0.00008379619,0.03381706,0.001083124],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9959371,0.0007831918,0.001169217,0.0005360731,0.0006137702,0.0006638378,0.0001051546,0.00005942176,0.0001322155],"genre_scores_gemma":[0.9872696,0.00875831,0.0001325179,0.001938731,0.0009723452,0.0001946332,0.000618214,0.0001102607,0.000005351549],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.4147667,"threshold_uncertainty_score":0.9995591,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01542146579656227,"score_gpt":0.2417422247301616,"score_spread":0.2263207589335993,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}