{"id":"W2887872046","doi":"10.1002/ange.201806823","title":"Innenrücktitelbild: Chemoenzymatic Synthesis of Advanced Intermediates for Formal Total Syntheses of Tetrodotoxin (Angew. Chem. 34/2018)","year":2018,"lang":"en","type":"article","venue":"Angewandte Chemie","topic":"Marine Toxins and Detection Methods","field":"Environmental Science","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Brock University","funders":"","keywords":"Tetrodotoxin; Chemistry; Stereochemistry; Biophysics; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0005030169,0.0002097642,0.0004167735,0.00007094419,0.00007746303,0.00001106593,0.0002765278,0.0001032365,0.002133342],"category_scores_gemma":[0.001430035,0.0001793616,0.0001747743,0.000279096,0.00048626,0.0002815917,0.0002496687,0.00007811223,0.00002964913],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00008547306,"about_ca_system_score_gemma":0.00001384807,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001096128,"about_ca_topic_score_gemma":0.00004944273,"domain_scores_codex":[0.9985831,0.00002591762,0.0004680481,0.0003089471,0.0002570896,0.0003568886],"domain_scores_gemma":[0.9985693,0.0005853034,0.0003023342,0.0003980196,0.00004390554,0.000101205],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002135523,0.0001464048,0.003413011,0.0002371644,0.0000426424,5.622289e-7,0.0002985989,0.00001053679,0.948559,0.00002201129,0.001306942,0.04574957],"study_design_scores_gemma":[0.0003025933,0.0002575746,0.002831952,0.00007923847,0.00004206587,0.000007544368,0.0002254406,0.000134836,0.9920455,0.0001946277,0.003682663,0.0001959974],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9686978,0.00004725816,0.001165706,0.00006442444,0.0001979021,0.0003734583,0.00005522273,0.00004934935,0.0293489],"genre_scores_gemma":[0.9743436,0.0000203315,0.02459351,0.00004652902,0.000139582,0.0001119585,0.000004338684,0.00002830567,0.0007118278],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.04555358,"threshold_uncertainty_score":0.9987788,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01508110852679907,"score_gpt":0.2628412226594679,"score_spread":0.2477601141326689,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}