{"id":"W2887944091","doi":"10.1158/1078-0432.ccr-18-1244","title":"A Clinical and Molecular Phase II Trial of Oral ENMD-2076 in Ovarian Clear Cell Carcinoma (OCCC): A Study of the Princess Margaret Phase II Consortium","year":2018,"lang":"en","type":"article","venue":"Clinical Cancer Research","topic":"Chromatin Remodeling and Cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":67,"is_retracted":false,"has_abstract":true,"ca_institutions":"Alberta Cancer Foundation; Princess Margaret Cancer Centre; BC Cancer Agency; Ottawa Hospital; University of Toronto; University Health Network","funders":"Princess Margaret Cancer Foundation","keywords":"Medicine; Phases of clinical research; Clear cell carcinoma; Phase (matter); Oncology; Ovarian cancer; Internal medicine; Clinical trial; Carcinoma; Gynecology; Cancer; Chemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.004619926,0.000177416,0.0005674143,0.0000711233,0.0001875552,0.00001494272,0.0006062528,0.0003189044,0.00007459669],"category_scores_gemma":[0.0009318545,0.0001351569,0.00020992,0.0003412991,0.001549576,0.000005867041,0.001029828,0.0006609141,0.000001021477],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002448861,"about_ca_system_score_gemma":0.0008727969,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008636513,"about_ca_topic_score_gemma":0.0006617373,"domain_scores_codex":[0.9954529,0.001479646,0.001333956,0.0007374905,0.0005723534,0.0004236831],"domain_scores_gemma":[0.997968,0.000163193,0.0002822424,0.0009129309,0.0004830958,0.0001905617],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.336867,0.07259041,0.1680724,0.0004532948,0.0005986655,0.00007712973,0.002552045,0.0000490595,0.3388075,0.0001365211,0.006106944,0.07368909],"study_design_scores_gemma":[0.5122325,0.2050652,0.01684714,0.0002532373,0.0002357964,0.000006770023,0.0016424,0.002231318,0.2457731,0.0003486979,0.01459986,0.0007639209],"study_design_candidate":"randomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9971685,0.0005011633,0.00002879098,0.0002849319,0.0003711758,0.001258436,0.00004868389,0.000004287041,0.000334049],"genre_scores_gemma":[0.9987692,0.0002408923,0.0001060048,0.0001194317,0.0004431438,0.00008912469,0.00000708588,0.00002871984,0.0001964329],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1753656,"threshold_uncertainty_score":0.5709476,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1406527583221379,"score_gpt":0.5115108080783575,"score_spread":0.3708580497562196,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}