{"id":"W2888023575","doi":"10.1113/jp275998","title":"Autophagy and mitophagy flux in young and aged skeletal muscle following chronic contractile activity","year":2018,"lang":"en","type":"article","venue":"The Journal of Physiology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":137,"is_retracted":false,"has_abstract":true,"ca_institutions":"York University","funders":"Canadian Institutes of Health Research; Hospital for Sick Children; York University","keywords":"Mitophagy; Autophagy; Mitochondrion; Skeletal muscle; Cell biology; Flux (metallurgy); Biology; Mitochondrial biogenesis; Endocrinology; Internal medicine; Lysosome; Ageing; Chemistry; Medicine; Biochemistry; Apoptosis","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003565912,0.0001137755,0.0003630381,0.00007326732,0.00009256585,0.000006591406,0.0000810573,0.00007558104,0.0001187263],"category_scores_gemma":[0.00005579636,0.0000729255,0.00008390789,0.0000766724,0.0002422243,0.0001341184,0.00003707239,0.0003103596,0.000004202031],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004845641,"about_ca_system_score_gemma":0.00009866142,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004431415,"about_ca_topic_score_gemma":0.00004047385,"domain_scores_codex":[0.9991792,0.0001884593,0.0002118116,0.0001066371,0.0001059165,0.0002079039],"domain_scores_gemma":[0.9993711,0.0001905835,0.0001742162,0.0001440221,0.00003955679,0.00008056583],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0004281634,0.00009640806,0.0006838806,0.00001827586,0.0001334954,0.00004884895,0.000565202,0.000001135629,0.9926172,0.00002186377,0.000081313,0.005304248],"study_design_scores_gemma":[0.003069291,0.001081562,0.9175356,0.00005509198,0.0001041634,0.0002754249,0.0001116396,0.0001888222,0.07659405,0.000703081,0.0002105738,0.00007069846],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.996577,0.00256841,0.00002581243,0.0001879871,0.0003377418,0.0001195564,0.000001154742,0.000007503442,0.0001748692],"genre_scores_gemma":[0.9986681,0.0002500747,0.00003397977,0.0002254445,0.000718921,0.00000159029,5.921044e-7,0.00001195034,0.00008930428],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.9168517,"threshold_uncertainty_score":0.2973816,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009446010310928496,"score_gpt":0.2835355338206411,"score_spread":0.2740895235097126,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}