{"id":"W2888114482","doi":"10.18433/jpps28987","title":"Pharmacokinetics of Orally Administered Poly(Ethylene Oxide)-block-Poly(ε-Caprolactone) Micelles of Cyclosporine A in Rats: Comparison with Neoral®","year":2018,"lang":"en","type":"article","venue":"Journal of Pharmacy & Pharmaceutical Sciences","topic":"Advanced Drug Delivery Systems","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":11,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"King Saud University","keywords":"Pharmacokinetics; Cmax; Ethylene oxide; Micelle; Chemistry; Oral administration; Caprolactone; Pharmacology; Dosage form; Bioavailability; Chromatography; Copolymer; Organic chemistry; Medicine; Aqueous solution; Polymer","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002277415,0.0003735431,0.0003902532,0.0002766557,0.0001138636,0.0003210093,0.0001678959,0.0003473907,0.0007196626],"category_scores_gemma":[0.0003054438,0.0001791608,0.0002670575,0.0001254786,0.0002867562,0.0004573017,0.00008658622,0.0006467578,0.0003459147],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002918085,"about_ca_system_score_gemma":0.0004818043,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000657801,"about_ca_topic_score_gemma":0.0007238621,"domain_scores_codex":[0.9998676,0.00002453442,0.000008646997,0.00003715189,0.00003431329,0.00002775756],"domain_scores_gemma":[0.9996775,0.00003577199,0.0001335893,0.00003099539,0.00003939992,0.00008269963],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.006518233,0.0006677252,0.001601972,0.00009743941,0.00003656575,0.00009803511,0.00005972568,0.0003841456,0.9805906,0.00005602378,0.0001109632,0.009778525],"study_design_scores_gemma":[0.0002853707,0.023452,0.015359,0.00001364648,0.0001304485,0.0004364862,0.0001031532,0.003041509,0.9545832,0.00006386565,0.002504029,0.00002728507],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9965061,0.001383798,0.001283174,0.00007471859,0.00003223404,0.00003003764,0.0001679157,0.00007937295,0.0004427297],"genre_scores_gemma":[0.9936106,0.001666358,0.001651994,0.0000813498,0.00004048313,0.0000689362,0.000323438,0.00003215519,0.002524578],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007196626,"threshold_uncertainty_score":0.002407551,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1571179000331498,"score_gpt":0.4791947240000268,"score_spread":0.322076823966877,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}