{"id":"W2888125032","doi":"10.1039/c8ra05728a","title":"Structural modification of oridonin <i>via</i> DAST induced rearrangement","year":2018,"lang":"en","type":"article","venue":"RSC Advances","topic":"Bioactive Natural Diterpenoids Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":11,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute of Cancer Research","funders":"National Natural Science Foundation of China-Shandong Joint Fund for Marine Science Research Centers; Fundamental Research Funds for the Central Universities; National Natural Science Foundation of China-Shandong Joint Fund; National Natural Science Foundation of China","keywords":"Chemistry; Stereochemistry; Epoxy; Terpenoid; Combinatorial chemistry; Organic chemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008732585,0.00009079441,0.00009033337,0.00003406513,0.00005612828,0.000008938541,0.000188236,0.00008062166,0.00003105372],"category_scores_gemma":[0.00005504143,0.00007523652,0.00003620967,0.0001100789,0.0001536142,0.00001217644,0.0000771913,0.00007384983,0.00001248939],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001480835,"about_ca_system_score_gemma":0.00002430816,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001961648,"about_ca_topic_score_gemma":0.00002660458,"domain_scores_codex":[0.9992371,0.00004050347,0.0001342234,0.0002434535,0.0001782883,0.0001663814],"domain_scores_gemma":[0.9993989,0.000007123218,0.00007939133,0.0002465232,0.0002258126,0.00004226532],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001157488,0.00001213687,0.0009511811,0.00001376342,0.00001352464,1.934133e-7,0.00002521369,0.000002936202,0.9515243,0.00009969714,0.0001767654,0.04706451],"study_design_scores_gemma":[0.0002496321,0.0004231705,0.006490238,0.00000797067,0.00000407895,0.000002073761,0.00003653757,0.0001478383,0.978687,0.000138161,0.01371559,0.00009770424],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9950347,0.001565683,0.001348523,0.0001039838,0.0001725673,0.0001690707,0.00001984919,0.000007673428,0.001577945],"genre_scores_gemma":[0.997848,0.0001359209,0.001309797,0.00004548545,0.0002972187,0.0000108498,0.0000637909,0.000009837873,0.0002790935],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.04696681,"threshold_uncertainty_score":0.3068056,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02624344438036756,"score_gpt":0.3372857787736879,"score_spread":0.3110423343933204,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}