{"id":"W2888161369","doi":"10.1016/j.pharmthera.2018.08.005","title":"Air pollution and resistance to inhaled glucocorticoids: Evidence, mechanisms and gaps to fill","year":2018,"lang":"en","type":"review","venue":"Pharmacology & Therapeutics","topic":"Air Quality and Health Impacts","field":"Environmental Science","cited_by":40,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of British Columbia","funders":"Canadian Institutes of Health Research; Mitacs; AllerGen; Canada Research Chairs; Michael Smith Health Research BC","keywords":"Asthma; Glucocorticoid; Air pollution; Glucocorticoid receptor; Medicine; Environmental health; Pollution; Tobacco smoke; Immunology; Biology; Ecology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001514411,0.0007114828,0.002285295,0.001590412,0.0002419568,0.0018604,0.0009634037,0.001430814,0.003683923],"category_scores_gemma":[0.002767935,0.0002789167,0.001192801,0.002194647,0.0006111105,0.001280761,0.0007388072,0.001942517,0.000678656],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005170726,"about_ca_system_score_gemma":0.002387617,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001813048,"about_ca_topic_score_gemma":0.004190237,"domain_scores_codex":[0.9995137,0.0001033352,0.0001062388,0.000089139,0.0001501044,0.00003733047],"domain_scores_gemma":[0.9980224,0.001332164,0.0002764185,0.00003740242,0.0002766724,0.00005499798],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0002841611,0.0001158021,0.001716927,0.06940798,0.0008667826,0.0001977471,0.0001036873,0.0003862086,0.0009100348,0.003842975,0.01658222,0.9055854],"study_design_scores_gemma":[0.0001360497,0.0003690334,0.0094156,0.04469405,0.003676117,0.002252722,0.0005181952,0.0003432189,0.0008199495,0.007234639,0.9304491,0.00009125777],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00007250486,0.9994352,0.00003014475,0.0002340012,0.0000606251,0.000001731554,0.00001736426,0.000001413935,0.0001468714],"genre_scores_gemma":[0.0008405414,0.9987135,0.00007597759,0.0001473416,0.0001421045,0.000002428784,0.000017288,4.577831e-7,0.00006052663],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.003683923,"threshold_uncertainty_score":0.01232398,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1268597481005913,"score_gpt":0.4199678735962697,"score_spread":0.2931081254956784,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}