{"id":"W2888175508","doi":"10.3390/cancers10080274","title":"Genetics and Expression Profile of the Tubulin Gene Superfamily in Breast Cancer Subtypes and Its Relation to Taxane Resistance","year":2018,"lang":"en","type":"article","venue":"Cancers","topic":"Microtubule and mitosis dynamics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":127,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"Cure Brain Cancer Foundation; Canadian Institutes of Health Research; Women and Children's Health Research Institute; Children's Health Research Institute","keywords":"Taxane; Tubulin; Biology; Paclitaxel; Gene isoform; Microtubule; Gene; Mitosis; Gene expression; Cancer research; Molecular biology; Cancer; Genetics; Breast cancer","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00005683458,0.00007555851,0.00007798563,0.00001965533,0.0000424708,0.000005417148,0.00007602842,0.0000794708,0.000008799453],"category_scores_gemma":[0.00001281552,0.00006077268,0.0000129862,0.0000791839,0.00006950998,0.000003073271,0.00007558375,0.00004043715,5.09174e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004867183,"about_ca_system_score_gemma":0.0001202113,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00009359763,"about_ca_topic_score_gemma":0.0007503977,"domain_scores_codex":[0.9994885,0.00002437572,0.0001127654,0.0002074582,0.00005524694,0.0001116808],"domain_scores_gemma":[0.9996927,0.000003522863,0.00004649453,0.0001511992,0.00006807407,0.00003795573],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001067239,0.000003089432,0.01560283,0.0000232295,0.000005290404,1.425854e-7,0.0001575375,0.00008415183,0.9826853,0.000008158206,0.0006887931,0.0006347835],"study_design_scores_gemma":[0.0002833648,0.00004256929,0.1096764,0.00008634404,0.000007622546,0.000002377104,0.00003975426,0.0002365361,0.8868664,0.000007509181,0.002659177,0.00009195956],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9948166,0.004491272,0.00004922644,0.000158095,0.00009404476,0.0001979716,0.00009325486,0.000001956085,0.00009757376],"genre_scores_gemma":[0.9969316,0.002030781,0.0003313362,0.0001779869,0.0000940798,0.00002402352,0.000007892527,0.00001038524,0.0003919415],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.09581887,"threshold_uncertainty_score":0.2478238,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006601734407825632,"score_gpt":0.2319535970560586,"score_spread":0.2253518626482329,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}