{"id":"W2888195361","doi":"10.1002/hep.30224","title":"The NACSTOP Trial: A Multicenter, Cluster‐Controlled Trial of Early Cessation of Acetylcysteine in Acetaminophen Overdose","year":2018,"lang":"en","type":"article","venue":"Hepatology","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":39,"is_retracted":false,"has_abstract":true,"ca_institutions":"Queen's University","funders":"National Health and Medical Research Council; Medical Research Council","keywords":"Medicine; Acetaminophen; Acetylcysteine; acetaminophen overdose; Interquartile range; Incidence (geometry); Regimen; Adverse effect; Internal medicine; Anesthesia; Gastroenterology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002454023,0.0002234438,0.0007819295,0.0002190748,0.0002137371,0.00001000291,0.0003519924,0.000653567,0.0001380168],"category_scores_gemma":[0.000752849,0.0001751117,0.0001985082,0.0003481285,0.0005642796,0.0001292221,0.0001070954,0.0006287341,0.00003829137],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00009111387,"about_ca_system_score_gemma":0.0001649966,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004738315,"about_ca_topic_score_gemma":0.001039692,"domain_scores_codex":[0.995508,0.002393343,0.001145827,0.0003108566,0.0002008194,0.0004411364],"domain_scores_gemma":[0.9971027,0.001475865,0.0007749541,0.0003416878,0.0002215997,0.00008319059],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9567692,0.001101461,0.007891578,0.00006145696,0.0002356329,0.000006090066,0.001989807,0.00001642916,0.01944269,0.001330363,0.0001731369,0.01098216],"study_design_scores_gemma":[0.9124883,0.003871159,0.0006094252,0.00002729509,0.0001761598,0.000009185308,0.0001319424,0.01088799,0.05930131,0.000786431,0.01149952,0.0002112958],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.988275,0.0001844884,0.0000898853,0.0007422581,0.004407205,0.004208423,0.00001557111,0.00003683038,0.002040374],"genre_scores_gemma":[0.9980966,0.000194083,0.00005422538,0.0002847543,0.0005059884,0.0004649137,0.000006416603,0.00001979045,0.0003732555],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.04428092,"threshold_uncertainty_score":0.7140846,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.09325552395835801,"score_gpt":0.4184533866972354,"score_spread":0.3251978627388774,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}