{"id":"W2888195361","doi":"10.1002/hep.30224","title":"The NACSTOP Trial: A Multicenter, Cluster‐Controlled Trial of Early Cessation of Acetylcysteine in Acetaminophen Overdose","year":2018,"lang":"en","type":"article","venue":"Hepatology","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":39,"is_retracted":false,"has_abstract":true,"ca_institutions":"Queen's University","funders":"National Health and Medical Research Council; Medical Research Council","keywords":"Medicine; Acetaminophen; Acetylcysteine; acetaminophen overdose; Interquartile range; Incidence (geometry); Regimen; Adverse effect; Internal medicine; Anesthesia; Gastroenterology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001222815,0.001136218,0.002139111,0.0003555869,0.0004783538,0.0008066365,0.0008751621,0.00123712,0.002949654],"category_scores_gemma":[0.001466638,0.0003031693,0.0009276413,0.0003904069,0.0009211794,0.0007323034,0.0004277574,0.002157692,0.0005499431],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006177942,"about_ca_system_score_gemma":0.001494094,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001452569,"about_ca_topic_score_gemma":0.003526455,"domain_scores_codex":[0.9994674,0.0003071262,0.00002865114,0.0000882715,0.00005102063,0.00005761316],"domain_scores_gemma":[0.9990667,0.0002163512,0.0002227851,0.00008287759,0.00008787752,0.0003234192],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9734518,0.007196268,0.001098774,0.0004823482,0.0004809714,0.00004302217,0.00005631488,0.0003241712,0.002076982,0.0001294924,0.001118014,0.01354188],"study_design_scores_gemma":[0.9320139,0.06303014,0.002981524,0.00004834845,0.0002279488,0.00004132367,0.00003251842,0.0004707495,0.0002839568,0.000114896,0.0007383658,0.00001623587],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9934132,0.002149406,0.0003072114,0.0005084377,0.0002688551,0.001469102,0.0005447886,0.00007156582,0.001267644],"genre_scores_gemma":[0.9883515,0.001899351,0.001696196,0.001054519,0.0003735109,0.003094406,0.001184167,0.00002444517,0.002321919],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002949654,"threshold_uncertainty_score":0.009867609,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.09325552395835801,"score_gpt":0.4184533866972354,"score_spread":0.3251978627388774,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}