{"id":"W2888202523","doi":"10.1093/cid/ciy696","title":"Definitions of Resistant and Refractory Cytomegalovirus Infection and Disease in Transplant Recipients for Use in Clinical Trials","year":2018,"lang":"en","type":"article","venue":"Clinical Infectious Diseases","topic":"Cytomegalovirus and herpesvirus research","field":"Medicine","cited_by":243,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Sanofi Pasteur; University of Texas MD Anderson Cancer Center; National Institutes of Health; AiCuris; Genentech; Danmarks Grundforskningsfond; U.S. Food and Drug Administration; National Cancer Institute; National Research Foundation; Viropharma; Sanofi; Astellas Pharma; Wellcome Trust; GlaxoSmithKline","keywords":"Medicine; Refractory (planetary science); Cytomegalovirus infection; Clinical trial; Cytomegalovirus; Cytomegalovirus infections; Disease; Intensive care medicine; Internal medicine; Immunology; Transplantation; Virology; Viral disease; Human cytomegalovirus; Herpesviridae; Virus","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaresearch"],"consensus_categories":[],"category_scores_codex":[0.004087431,0.0002063196,0.001180955,0.0004775888,0.0001002548,0.00004932054,0.00005248366,0.0002559594,0.0000547866],"category_scores_gemma":[0.02308139,0.0001767224,0.0003723657,0.0003660476,0.0009128267,0.0002211028,0.00005716289,0.0004289335,0.000007883156],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00007778113,"about_ca_system_score_gemma":0.0004290804,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000612893,"about_ca_topic_score_gemma":0.003086072,"domain_scores_codex":[0.9955853,0.001076268,0.002156504,0.0006058507,0.000233486,0.0003426202],"domain_scores_gemma":[0.990686,0.007520356,0.0003254959,0.0003605496,0.0002338131,0.0008738108],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.008315288,0.002741265,0.9763395,0.0001831088,0.00009263004,0.00003580315,0.00003995694,6.720664e-7,0.00008110605,0.0005527522,0.0003507383,0.01126719],"study_design_scores_gemma":[0.008512092,0.002432133,0.9824886,0.0005196224,0.0003184109,0.000002300804,0.000007724398,0.0003027239,0.0000134946,0.003383918,0.001846661,0.0001722788],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9968631,0.0006054985,0.00009427051,0.0001625419,0.000290325,0.001298081,0.0005118166,0.00004308685,0.0001313362],"genre_scores_gemma":[0.98643,0.01255374,0.00005309403,0.0003354753,0.0003649019,0.0001418689,0.0000672701,0.00003007887,0.00002353116],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01899396,"threshold_uncertainty_score":0.9851476,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.2667376065125183,"score_gpt":0.4753510775794814,"score_spread":0.2086134710669631,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}