{"id":"W2888244195","doi":"10.15252/msb.20178129","title":"Proteome‐wide analysis of phospho‐regulated PDZ domain interactions","year":2018,"lang":"en","type":"article","venue":"Molecular Systems Biology","topic":"Hippo pathway signaling and YAP/TAZ","field":"Biochemistry, Genetics and Molecular Biology","cited_by":77,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Vetenskapsrådet; Knut och Alice Wallenbergs Stiftelse; Science for Life Laboratory; Carl Tryggers Stiftelse för Vetenskaplig Forskning; University of Toronto; Institut National de la Santé et de la Recherche Médicale; Åke Wiberg Stiftelse; Wenner-Gren Foundation","keywords":"PDZ domain; Biology; Proteome; Computational biology; Domain (mathematical analysis); Cell biology; Bioinformatics","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000145545,0.0001435209,0.0002157914,0.0003656744,0.0001983377,0.0002560941,0.0001377892,0.0001698109,0.0007908604],"category_scores_gemma":[0.0001183284,0.000088706,0.0001344037,0.0004190469,0.0001161658,0.000131055,0.0001666518,0.0003767717,0.0002034817],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002124534,"about_ca_system_score_gemma":0.0001071723,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003822522,"about_ca_topic_score_gemma":0.0007863423,"domain_scores_codex":[0.9998988,0.000007668378,0.000004183974,0.00004157764,0.0000323619,0.00001547184],"domain_scores_gemma":[0.9999421,0.00001242005,0.00001593116,0.000004138162,0.000009831008,0.00001557683],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00007014303,0.00001453006,0.001097383,0.00002644436,0.00001022705,0.00002049958,0.00001369898,0.00009416677,0.9974396,0.00005134055,0.0000601598,0.001101788],"study_design_scores_gemma":[0.0000200114,0.0001442135,0.1301454,0.000005282137,0.0000417958,0.0003811895,0.00008054547,0.006204314,0.8591105,0.0001589989,0.003693973,0.00001383463],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9919391,0.0006905062,0.004213285,0.00005359352,0.00000947252,0.00001996701,0.00232858,0.00008556154,0.0006599852],"genre_scores_gemma":[0.9893898,0.0005493313,0.005875832,0.00006929895,0.000008116976,0.00005220802,0.002940963,0.00002275715,0.001091531],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007908604,"threshold_uncertainty_score":0.002645731,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007918673375256901,"score_gpt":0.2613083125371757,"score_spread":0.2533896391619188,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}