{"id":"W2888244195","doi":"10.15252/msb.20178129","title":"Proteome‐wide analysis of phospho‐regulated PDZ domain interactions","year":2018,"lang":"en","type":"article","venue":"Molecular Systems Biology","topic":"Hippo pathway signaling and YAP/TAZ","field":"Biochemistry, Genetics and Molecular Biology","cited_by":77,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Vetenskapsrådet; Knut och Alice Wallenbergs Stiftelse; Science for Life Laboratory; Carl Tryggers Stiftelse för Vetenskaplig Forskning; University of Toronto; Institut National de la Santé et de la Recherche Médicale; Åke Wiberg Stiftelse; Wenner-Gren Foundation","keywords":"PDZ domain; Biology; Proteome; Computational biology; Domain (mathematical analysis); Cell biology; Bioinformatics","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003770554,0.0002278262,0.000469687,0.0002956901,0.00009255686,0.00001795185,0.0002858587,0.0002925028,0.00005769478],"category_scores_gemma":[0.0001176339,0.0002070479,0.0002990568,0.0006695603,0.0002700013,0.000002846936,0.0001031294,0.0001032528,0.00003512158],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002265935,"about_ca_system_score_gemma":0.00007377824,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000300301,"about_ca_topic_score_gemma":0.00009181893,"domain_scores_codex":[0.9981609,0.0003416297,0.0005066525,0.0005347149,0.0001099765,0.0003461538],"domain_scores_gemma":[0.9986201,0.00002120852,0.0002669808,0.0006888895,0.0003003151,0.000102499],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00007530674,0.00005888347,0.002818293,0.00001683369,0.001464013,0.000006812099,0.00008572709,0.0001949509,0.9944842,0.0004949534,0.000097565,0.0002024768],"study_design_scores_gemma":[0.0004354712,0.0006701324,0.0008978483,0.00003177833,0.0003476871,0.00002284784,0.0001007239,0.0008946516,0.9538175,0.00008712615,0.04238165,0.0003125757],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9408777,0.0008155077,0.05595915,0.00006838643,0.0004494646,0.0003221743,0.00007913781,0.0000303144,0.001398174],"genre_scores_gemma":[0.9980556,0.00001018945,0.0005826235,0.0001245697,0.0001557425,0.00006977699,0.000450461,0.00002791867,0.0005231031],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.05717793,"threshold_uncertainty_score":0.8443167,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007918673375256901,"score_gpt":0.2613083125371757,"score_spread":0.2533896391619188,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}