{"id":"W2888273939","doi":"10.1016/j.bbamem.2018.08.011","title":"Effect of late endosomal DOBMP lipid and traditional model lipids of electrophysiology on the anthrax toxin channel activity","year":2018,"lang":"en","type":"article","venue":"Biochimica et Biophysica Acta (BBA) - Biomembranes","topic":"Bacillus and Francisella bacterial research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Calgary","funders":"Catholic University of America; National Institutes of Health; Catholic University of Korea; National Institute of Allergy and Infectious Diseases; Natural Sciences and Engineering Research Council of Canada; Canada Research Chairs","keywords":"Anthrax toxin; Lipid bilayer; Biophysics; Endosome; Membrane; Cytosol; Chemistry; Vesicle; Toxin; Biochemistry; Ion channel; Gating; Transmembrane channels; Enzyme; Biology; Fusion protein; Voltage-gated ion channel; Cell; Receptor; Recombinant DNA","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004365965,0.0004787502,0.0003613972,0.0001721728,0.0002683063,0.000516605,0.000401877,0.0005848107,0.003350554],"category_scores_gemma":[0.001204038,0.0001961119,0.0001863844,0.0002567312,0.0005715875,0.0008839703,0.0003338817,0.0007578922,0.0004149701],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003745729,"about_ca_system_score_gemma":0.0004912391,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001112917,"about_ca_topic_score_gemma":0.0006409819,"domain_scores_codex":[0.9997539,0.00007167459,0.00002490832,0.00003893663,0.00002938099,0.00008118736],"domain_scores_gemma":[0.9991658,0.0004535516,0.00005840222,0.00006501545,0.00008041493,0.0001768936],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.007590733,0.0001892526,0.0002720008,0.0001403936,0.00002493446,0.0001803462,0.0001829029,0.0001469822,0.9889313,0.000528328,0.0001150096,0.001697834],"study_design_scores_gemma":[0.0001529864,0.0005727542,0.001061188,0.00001015678,0.00002877709,0.00008086828,0.00006277095,0.0005597609,0.9964754,0.00008757098,0.0008985561,0.000009180761],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9966823,0.0008130542,0.0005998244,0.000140478,0.00004774642,0.00001992338,0.0001868298,0.00003134809,0.001478351],"genre_scores_gemma":[0.996357,0.0006702298,0.0008478326,0.00009258132,0.00002828525,0.00003008337,0.0003314579,0.00003092657,0.001611553],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003350554,"threshold_uncertainty_score":0.01120871,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01782216483150744,"score_gpt":0.2629080732569704,"score_spread":0.2450859084254629,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}