{"id":"W2888387114","doi":"10.1016/j.exphem.2018.06.038","title":"Translating human development to new therapies with pluripotent stem cells","year":2018,"lang":"en","type":"article","venue":"Experimental Hematology","topic":"Pluripotent Stem Cells Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"University Health Network","funders":"","keywords":"Mesoderm; Induced pluripotent stem cell; Biology; Wnt signaling pathway; Nodal signaling; Stem cell; Cell biology; Haematopoiesis; NODAL; Signal transduction; Genetics; Embryonic stem cell; Bioinformatics; Cancer research; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002656169,0.0005330632,0.0004573329,0.0004935763,0.0003062904,0.002677259,0.0005954008,0.0009363841,0.01006477],"category_scores_gemma":[0.001883634,0.0001927083,0.0003816536,0.0003004622,0.002236241,0.001694049,0.001375172,0.001958074,0.001284572],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0009854072,"about_ca_system_score_gemma":0.00164984,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004822469,"about_ca_topic_score_gemma":0.0005453416,"domain_scores_codex":[0.9994165,0.0002366703,0.00003727977,0.00006977835,0.0001688975,0.00007087463],"domain_scores_gemma":[0.9991279,0.0005069292,0.00007197504,0.0001054476,0.000109847,0.00007795683],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"theoretical_or_conceptual","study_design_gemma":"theoretical_or_conceptual","study_design_scores_codex":[0.0006976211,0.0004470913,0.001794147,0.001448945,0.0001112039,0.0004436384,0.000622693,0.003283363,0.1474712,0.5024287,0.01831796,0.3229335],"study_design_scores_gemma":[0.0002490819,0.001300552,0.001970908,0.000741764,0.0001755221,0.0005435341,0.0008749682,0.00234322,0.2181304,0.2887115,0.4849191,0.00003951623],"study_design_candidate":"theoretical_or_conceptual","study_design_consensus":"theoretical_or_conceptual","genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.130878,0.2823187,0.2627946,0.1188425,0.01347878,0.000634403,0.001545384,0.0009664953,0.1885411],"genre_scores_gemma":[0.6147937,0.2338229,0.09654795,0.01809996,0.004273523,0.0004286341,0.001000153,0.0002678142,0.03076529],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.01006477,"threshold_uncertainty_score":0.03366995,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02455829262355096,"score_gpt":0.3002321535348562,"score_spread":0.2756738609113052,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}