{"id":"W2888395668","doi":"10.1038/s41398-018-0194-7","title":"Neurofilament light interaction with GluN1 modulates neurotransmission and schizophrenia-associated behaviors","year":2018,"lang":"en","type":"article","venue":"Translational Psychiatry","topic":"Skin and Cellular Biology Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":55,"is_retracted":false,"has_abstract":true,"ca_institutions":"Centre hospitalier de l'Université Laval","funders":"National Center for Research Resources; National Institute on Aging; National Institutes of Health; National Institute on Alcohol Abuse and Alcoholism; U.S. Department of Health and Human Services","keywords":"Neuroscience; Hippocampal formation; NMDA receptor; Long-term potentiation; Schizophrenia (object-oriented programming); Neurotransmission; Hippocampus; Glutamate receptor; Psychology; Prepulse inhibition; Psychosis; Synaptic plasticity; Medicine; Psychiatry; Receptor; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00005658096,0.0002721199,0.0001312774,0.0001013111,0.0001359738,0.0001612748,0.0001056051,0.0001772685,0.0007453081],"category_scores_gemma":[0.0000540421,0.00007574323,0.00009823804,0.00006026001,0.0001681401,0.000122141,0.0001478427,0.0002228662,0.0001120565],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003112561,"about_ca_system_score_gemma":0.0001219845,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009172484,"about_ca_topic_score_gemma":0.001551582,"domain_scores_codex":[0.9999459,0.000007671657,0.000002862504,0.0000139099,0.00001224759,0.00001740855],"domain_scores_gemma":[0.9999481,0.000001867824,0.00002645579,0.000002106195,0.000004131306,0.00001722253],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000147122,0.00001413401,0.0009331902,0.00001693723,0.000005044181,0.00004609491,0.000009423088,0.00001555299,0.9977881,0.00004502888,0.00001652421,0.0009629069],"study_design_scores_gemma":[0.00003630918,0.0004077447,0.1654394,0.00001978016,0.00004054276,0.0006492753,0.000114421,0.001106302,0.8301339,0.0002146756,0.001827455,0.00001023123],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9977677,0.001122104,0.000405798,0.00006531916,0.000005224254,0.000003193054,0.00006831374,0.00001609237,0.0005462611],"genre_scores_gemma":[0.998356,0.0005531744,0.0002716337,0.00002691218,0.000002737527,0.000005498503,0.00007193624,0.000003385152,0.0007085644],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009172484,"threshold_uncertainty_score":0.002493262,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01021902211334916,"score_gpt":0.27271715727519,"score_spread":0.2624981351618408,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}