{"id":"W2888420880","doi":"10.1016/j.gene.2018.08.066","title":"Identification of essential yeast genes involved in polyamine resistance","year":2018,"lang":"en","type":"article","venue":"Gene","topic":"Polyamine Metabolism and Applications","field":"Biochemistry, Genetics and Molecular Biology","cited_by":6,"is_retracted":false,"has_abstract":false,"ca_institutions":"Hôpital Maisonneuve-Rosemont; Université de Montréal","funders":"Canadian Institutes of Health Research","keywords":"Biology; Polyamine; Spermidine; Spermine; Biochemistry; Gene; DNA; Saccharomyces cerevisiae; RNA; Mutant; DNA damage; Molecular biology; Cell biology; Enzyme","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001358132,0.0005544247,0.0003697412,0.0005279274,0.0001523924,0.0003289369,0.0003238481,0.0003499507,0.0009774547],"category_scores_gemma":[0.000208822,0.0001782113,0.0003790706,0.0003541158,0.0002802489,0.000192593,0.0003413463,0.0006209721,0.0005410864],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002620579,"about_ca_system_score_gemma":0.0003251251,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005337399,"about_ca_topic_score_gemma":0.000729429,"domain_scores_codex":[0.9999214,0.000009838458,0.000009859705,0.00001956033,0.00002302823,0.00001623821],"domain_scores_gemma":[0.9997768,0.00006018758,0.00003701873,0.00003178297,0.0000368959,0.0000572789],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001026862,0.00002515266,0.000305704,0.00003294395,0.000002955413,0.00008742153,0.00001099205,0.00003756147,0.9973738,0.0001427537,0.00002512096,0.001852813],"study_design_scores_gemma":[0.00001332426,0.0001341094,0.006513704,0.000008853661,0.00003452568,0.0005738595,0.00006852565,0.000699782,0.9892722,0.0001792937,0.002496175,0.000005552969],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9710978,0.002282919,0.0217106,0.0002473542,0.00005848986,0.00009953171,0.002427255,0.0003015669,0.001774531],"genre_scores_gemma":[0.9709702,0.001841911,0.0177415,0.00008545953,0.00001581449,0.00005294147,0.005845549,0.0001026079,0.003343993],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009774547,"threshold_uncertainty_score":0.003269911,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007394076718286252,"score_gpt":0.2526244842103646,"score_spread":0.2452304074920783,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}