{"id":"W2888450494","doi":"10.1097/moh.0000000000000464","title":"Next-generation sequencing-based minimal residual disease monitoring in patients receiving allogeneic hematopoietic stem cell transplantation for acute myeloid leukemia or myelodysplastic syndrome","year":2018,"lang":"en","type":"review","venue":"Current Opinion in Hematology","topic":"Acute Myeloid Leukemia Research","field":"Medicine","cited_by":25,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; Princess Margaret Cancer Centre; University Health Network","funders":"","keywords":"Minimal residual disease; Medicine; Myelodysplastic syndromes; Myeloid leukemia; Oncology; Hematopoietic stem cell transplantation; Transplantation; Clinical trial; Internal medicine; Leukemia; Myeloid; Stem cell; Disease; Immunology; Bone marrow; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0007097725,0.0009556242,0.002821878,0.001627913,0.0001544897,0.00007240909,0.0005043665,0.0008103536,0.00003662649],"category_scores_gemma":[0.0002672686,0.0008368948,0.0004213574,0.0009663826,0.0001850095,0.0002443643,0.0001086319,0.001109035,0.00007043846],"about_ca_system_candidate":true,"about_ca_system_consensus":true,"about_ca_system_score_codex":0.004172424,"about_ca_system_score_gemma":0.006114482,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001031439,"about_ca_topic_score_gemma":0.00001138582,"domain_scores_codex":[0.9938024,0.0006846472,0.002109252,0.001520264,0.000708987,0.001174444],"domain_scores_gemma":[0.9965973,0.001165021,0.0007658344,0.0007308015,0.0002849558,0.0004560729],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"systematic_review","study_design_gemma":"systematic_review","study_design_scores_codex":[0.006676476,0.001609971,0.02701554,0.7330368,0.0006939455,0.001228347,0.001422363,0.000242287,0.00007988978,0.0001139168,0.003328135,0.2245523],"study_design_scores_gemma":[0.06706955,0.01129891,0.0193944,0.7071233,0.01304044,0.005577843,0.0005948216,0.01882546,0.001252206,0.0001100128,0.1454357,0.01027736],"study_design_candidate":"systematic_review","study_design_consensus":"systematic_review","genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0758585,0.9069225,0.0009815702,0.00008032031,0.00772617,0.007878518,0.0004107913,0.0001352828,0.000006371609],"genre_scores_gemma":[0.01812308,0.9714469,0.0008613422,0.00001189193,0.0008822954,0.003046081,0.005331051,0.0002413869,0.00005602186],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.2142749,"threshold_uncertainty_score":0.9996504,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1508915042060647,"score_gpt":0.386555132357494,"score_spread":0.2356636281514293,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}